Trinity College Dublin
|As first author||15|
|As last author||23|
J V Reynolds(28)
Mary Clare Cathcart(9)
N J O'Farrell(6)
Elizabeth J Ryan(6)
Breandán N Kennedy(5)
Margaret R Dunne(5)
... and 119 others
These arethe14 unique sources for Jacintha O'Sullivan's 74 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.
|Ireland -> Dublin City University||2|
|Ireland -> Dublin City University -> PubMed||2|
|Ireland -> Dublin Institute of Technology||6|
|Ireland -> Dublin Institute of Technology -> PubMed||6|
|Ireland -> Maynooth University||1|
|Ireland -> Royal College of Surgeons in Ireland||2|
|Ireland -> TU Dublin||2|
|Ireland -> Trinity College Dublin||43|
|Ireland -> Trinity College Dublin -> PubMed||15|
|Ireland -> University College Cork||7|
|Ireland -> University College Cork -> PubMed||6|
|Ireland -> University College Dublin||13|
|Ireland -> University College Dublin -> PubMed||11|
|Ireland -> University of Limerick||3|
Compounds of the formula A-X-Y-B and compositions are described which are useful especially for treatment of angiogenesis-related diseases or disorders such as neovascularisation of the eye, age- related macular degeneration, diabetic retinopathy or cancer, wherein A is a six membered heteroaryl ring containing 2 nitrogen atoms which is optionally substituted with R1; R1 is H, CI-6 alkyl, CN, CONR2R3; R2 and R3 which may be the same or different and selected from H, CI-6 alkyl or R2 and R3 form a ring; the group X-Y is an alkyne or alkene, in the case wherein X-Y is an alkene the double bond may be cis or trans and optionally substituted with R1 B is an aryl; or five or six membered heteroaryl ring containing 1 to 3 heteroatoms, both of which may optionally substituted with one or more R4; R4 is R1 or OR5; R5 is H, COR6 or R6; and R6 is CI-6 alkyl and salts thereof.
(E)-2-(2-Quinolin-2-yl-propenyl)-phenol, 2-Quinolin-2-yl-ylethynyl-phenol and salts thereof are useful as medicaments, especially for treatment of an angiogenesis-related disease or disorder.
A styrylquinoline derivative of structure I or IV or a benzodioxol isoquinoline of structure II or III for use in the treatment of an angiogenesis-related disease or disorder. The invention also provides a composition comprising a styrylquinoline derivative of structure I or IV or a benzodioxol isoquinoline of structure II or III for use as a medicament.
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