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Kevin Kavanagh

Institution

Maynooth University

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Subjects

Microbiology

Details
Publications 183
As first author 8
As last author 88
Unique topics 713
Collaborations 104
Sources 13
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2016
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2020

In Vivo Activity of Copper(II), Manganese(II), and Silver(I) 1,10-Phenanthroline Chelates
2019

A new class of prophylactic metallo-antibiotic possessing potent anti-cancer and anti-microbial properties.
2018

Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans
2018

Analysis of the effect of temperature on protein abundance in Demodex-associated Bacillus oleronius.
2018

Characterisation of the cellular and proteomic response of Galleria mellonella larvae to the development of invasive aspergillosis
2018

Efficacy of entomopathogenic fungi against large pine weevil, Hylobius abietis, and their additive effects when combined with entomopathogenic nematodes
2018

Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes
2018

In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes
2018

Innate humoral immune defences in mammals and insects: The same, with differences ?
2018

Natural Product-Based 1,2,3-Triazole/Sulfonate Analogues as Potential Chemotherapeutic Agents for Bacterial Infections
2018

Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and 109Ag NMR studies
2018

Quantitative proteomics reveals divergent responses in Apis mellifera worker and drone pupae to parasitization by Varroa destructor
2018

The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus
2018

The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis
2018

Unprecedented
2018

Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10- Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs
2018

Unprecedented in Vitro Antitubercular Activity of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs
2017

Analysis of the acute response of Galleria mellonella larvae to potassium nitrate
2017

Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans.
2017

Caffeine administration alters the behaviour and development of Galleria mellonella larvae.
2017

Detection of Trichoderma aggressivum in bulk phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields
2017

Glycosylated metal chelators as anti-parasitic agents with tunable selectivity.
2017

In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes.
2017

Quantitative proteomics reveals divergent responses in Apis mellifera worker and drone pupae to parasitization by Varroa destructor.
2017

Steroid-Au(I) -NHC Complexes: Synthesis and Antibacterial Activity.
2017

The effect of entomopathogenic fungal culture filtrate on the immune response of the greater wax moth, Galleria mellonella.
2016

Activation of Neutrophils via IP3 Pathway Following Exposure to Demodex-Associated Bacterial Proteins
2016

Analysis of the acute response of Galleria mellonella larvae to potassium nitrate.
2016

Effect of novel triazole–amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies
2016

Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents.
2016

Evaluation of Galleria mellonella larvae for studying the virulence of Streptococcus suis.
2016

Novel silver(I) complexes of coumarin oxyacetate ligands and their phenanthroline adducts: Biological activity, structural and spectroscopic characterisation.
2016

Proteomic analysis of Bayvarol® resistance mechanisms in the honey bee parasite Varroa destructor
2016

Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea
2016

The role of altered cutaneous immune responses in the induction and persistence of rosacea
2015

Activation of Neutrophils via IP3 Pathway Following Exposure to Demodex-Associated Bacterial Proteins.
2015

Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance
2015

Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection
2015

Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea.
2015

The innate immune response to Aspergillus fumigatus at the alveolar surface.
2015

The role of altered cutaneous immune responses in the induction and persistence of rosacea.
2015

Trunk vertebrae osteomyelitis in a spectacled caiman (Caiman crocodilus)
2014

Assessment of in vivo antimicrobial activity of the carbene silver(I) acetate derivative SBC3 using Galleria mellonella larvae.
2014

Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients
2014

Exposure of a corneal epithelial cell line (hTCEpi) to Demodex-associated Bacillus proteins results in an inflammatory response.
2014

Isolation and characterisation of silver(I) complexes of substituted coumarin-4-carboxylates which are effective against Pseudomonas aeruginosa biofilms
2014

Proteomic response of Trichoderma aggressivum f. europaeum to Agaricus bisporus tissue and mushroom compost.
2014

Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives
2014

Thermal and physical stresses induce a short-term immune priming effect in Galleria mellonella larvae
2013

A new phenanthroline-oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction.
2013

An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes
2013

Developing the potential of using Galleria mellonella larvae as models for studying brain infection by Listeria monocytogenes
2013

Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin.
2013

Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bc deletion in Aspergillus fumigatus
2013

Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bγ deletion in Aspergillus fumigatus.
2013

Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities
2013

Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I)
2013

Synthesis, structure and biological activity of silver(I) complexes of substituted imidazoles
2012

Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea
2012

Demodex-associated bacterial proteins induce neutrophil activation
2012

Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection
2012

Exposure of Staphylococcus aureus to silver(I) induces a short term protective response.
2012

Galleria mellonella as a Model for Fungal Pathogenicity Testing
2012

Gliotoxin effects on fungal growth: Mechanisms and exploitation
2012

In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes
2012

Nonribosomal peptide synthetase genes pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus.
2012

Positive correlation between serum immunoreactivity to Demodex-associated Bacillus proteins and erythematotelangiectatic rosacea.
2012

Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I).
2012

Silver(I) complexes of 9-anthracenecarboxylic acid and imidazoles: synthesis, structure and antimicrobial activity
2012

The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis.
2012

The effect of Aspergillus fumigatus infection on vitamin D receptor expression in cystic fibrosis.
2012

The potential role of Demodex folliculorum mites and bacteria in the induction of rosacea
2011

Candida Urinary Tract Infection: Pathogenesis
2011

Caspofungin primes the immune response of the larvae of Galleria mellonella and induces a non-specific antimicrobial response
2011

Demodex-associated bacterial proteins induce neutrophil activation.
2011

Disruption of haemocyte function by exposure to cytochalasin b or nocodazole increases the susceptibility of Galleria mellonella larvae to infection
2011

Gliotoxin effects on fungal growth: mechanisms and exploitation.
2011

Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity
2011

Pre-exposure of Galleria mellonella larvae to different doses of Aspergillus fumigatus conidia causes differential activation of cellular and humoral immune responses
2011

Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry.
2011

Targeted disruption of nonribosomal peptide synthetase pes3 augments the virulence of Aspergillus fumigatus.
2011

The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes.
2011

The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus
2011

Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells
2011

Water-soluble CuII and MnII bis-phenanthroline octanedioate complexes with unprecedented nano and picomolar in vitro cytotoxicity as promising leads for chemotherapeutic drug development
2011

Water-soluble bis(1,10-phenanthroline) Octanedioate Cu2+ and Mn2+ Complexes with Unprecedented Nano and Picomolar in Vitro Cytotoxicity: Promising Leads for Chemotherapeutic Drug Development
2010

Analysis of the response of Candida albicans cells to Silver(I).
2010

Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases
2010

Correlation between Ocular Demodex Infestation and Serum Immunoreactivity to Bacillus Proteins in Patients with Facial Rosacea
2010

Dose-dependent cellular and humoral responses in Galleria mellonella larvae following β-glucan inoculation
2010

Galleria mellonella larvae as models for studying fungal virulence
2010

Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin.
2010

Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity.
2010

Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin.
2010

Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin
2010

The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus.
2010

Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells.
2009

Exposure to caspofungin activates Cap and Hog pathways in Candida albicans.
2009

Role of cell cycle events and apoptosis in mediating the anti-cancer activity of a silver(I) complex of 4-hydroxy-3-nitro-coumarin-bis(phenanthroline) in human malignant cancer cells.
2009

Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin.
2009

Under the lash: Demodex mites in human diseases
2009

Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]
2008

Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans
2008

Physical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans
2008

Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3].
2007

An in vitro investigation of the induction of apoptosis and modulation of cell cycle events in human cancer cells by bisphenanthroline-coumarin-6,7-dioxacetatocopper(II) complex
2007

Apoptotic cell death: A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa) (phen)2] (phen=phenanthroline, 4-Mecdoa=4-methylcoumarin-6, 7-dioxactetate), in human malignant cancer cells
2007

Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans.
2007

Epsilometer Test-Based Determination of Susceptibility of Clinically Important Candida Isolates to Conventional Antifungal Agents
2007

Insect and Mammalian Innate Immune Responses Are Much Alike
2007

Mechanism of action of coumarin and silver(I)- coumarin complexes against the pathogenic yeast Candida albicans
2007

Mite-related bacterial antigens stimulate inflammatory cells in rosacea
2007

Physical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans.
2007

Synthesis and structure of metal complexes containing zwitterionic N-hydroxyimidazole ligands
2007

Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2] · 8.8H2O and [Cu(4-Mecdoa)(phen)2] · 13H2O (phen = 1,10-phenanthroline)
2007

[Ag2(aca)2]n and [Ag4(aca)4(NH3)2] (acaH = 9-anthracenecarboxylic acid): Synthesis, X-ray crystal structures, antimicrobial and anti-cancer activities
2006

'Silver bullets' in antimicrobial chemotherapy: Synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes
2006

A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus.
2006

A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells.
2006

An in vitro investigation of the induction of apoptosis and modulation of cell cycle events in human cancer cells by bisphenanthroline-coumarin-6,7-dioxacetatocopper(II) complex.
2006

Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: Identification and characterisation of an elongation factor 1B protein with glutathione transferase activity
2006

Apoptotic cell death: a possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa)(phen)(2)] (phen=phenanthroline, 4-Mecdoa=4-methylcoumarin-6,7-dioxactetate), in human malignant cancer cells.
2006

Effect of N-chorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin
2006

In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines.
2006

Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus.
2006

Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans.
2006

Pre-exposure to yeast protects larvae of Galleria mellonellafrom a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides
2006

Susceptibility of Larvae of Galleria mellonella to Infection by Asperillus fumigatus is Dependent upon Stage of Conidial Germination
2006

Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenanthroline).
2006

Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(1) complexes
2006

Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes
2006

Translocation of proteins homologous to human neutrophilp47phox and p67phox to the cell membrane in activatedhemocytes of Galleria mellonella
2005

A 4'-Phosphopantetheinyl Transferase Mediates Non-Ribosomal Peptide Synthetase Activation in Aspergillus fumigatus
2005

Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus
2005

Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides.
2005

Superoxide Production in Galleria mellonella Hemocytes: Identification of Proteins Homologous to the NADPH Oxidase Complex of Human Neutrophils
2005

Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc)2(H2O)2] Æ 2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)
2005

The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron
2004

Amphotericin B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus
2004

Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella.
2004

Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development
2004

Exploiting the potential of Insects for in vivo pathogenicity testing of Microbial pathogen
2004

Histatins: antimicrobial peptides with therapeutic potential
2004

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes
2004

Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to Amphotericin B and Miconazole
2004

Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells.
2004

Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2(NH3)2(salH)2] (salH2 ¼salicylic acid)
2004

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(40-thiazolyl)benzimidazole{thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl • H2O • EtOH and TBZH2NO3 (TBZH¼thiabendazole)
2004

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4’-thiazolyl)benzimazole {thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH = thiabendazole)
2004

Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands
2003

Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B
2003

Erythromycin, an inhibitor of mitoribosomal protein biosynthesis, alters the amphotericin B susceptibility of Candida albicans
2003

Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B
2003

Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella.
2003

Isolation and identification of Madurella mycetomatis from two cases of black grain mycetoma in Libya
2003

Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes.
2003

Quantitative detection of C-reactive protein using phosphocholine-labelled enzyme or microspheres
2003

Synthesis and antimicrobial activity of (Z)-3-(1H-imidazol-1-yl)-2-phenylpropenenitrile and its metal complexes: X-ray crystal structures of the Zn(II) and Ag(I) complexes.
2003

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole).
2002

Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae
2002

Dermatophytes and other fungi associated with skin mycoses in Tripoli, Libya
2002

Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B.
2002

Immobilization of Aspergillus fumigatus colonies in a soft agar matrix allows visualization of A549 cell detachment and death.
2002

Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study
2001

Adherence of clinical isolates of Saccharomyces cerevisiae to buccal epithelial cells
2001

Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection
2001

Pulmonary aspergillosis: Clinical presentation, diagnosis and therapy
2001

Trichophyton violaceum is the dominant cause of tinea capitis in children in Tripoli, Libya: Results of a two year survey
2000

Adherence mechanisms of Candida albicans
2000

Development of an insect model for the in vivo pathogenicity testing of yeasts.
1999

Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines
1999

Emergence of Saccharomyces cerevisiae as a human pathogen Implications for biotechnology
1998

A rapid method for the extraction of whole cell proteins from Candida species
1998

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
1998

Monoclonal antibodies directed against extracellular matrix proteins reduce the adherence of Candida albicans to HEp-2 cells
1997

Membrane changes associated with the early stages of apoptosis in HEp-2 cells decrease susceptibility to adherence by Candida albicans
1996

Absence of correlation between chemo- and radioresistance in a range of human tumour cell lines.
1996

Application of protoplast fusion to the nonconventional yeast
1994

Analysis of hybrids of Candida albicans formed by protoplast fusion
1994

Application of the Melle-Boinot process to the fermentation of xylose by Pachysolen tannophilus
1992

Multiple transformation of Saccharomyces cerevisiae by protoplast fusion
1991

Enhanced intraspecific protoplast fusion in yeast
1991

Funcelase — An efficient preparation for the isolation of reversion competent protoplasts from yeasts

These arethe13 unique sources for Kevin Kavanagh's 183 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 5
Ireland -> Dublin City University -> PubMed 5
Ireland -> Dublin Institute of Technology 5
Ireland -> Dublin Institute of Technology -> PubMed 3
Ireland -> Maynooth University 168
Ireland -> Maynooth University -> PubMed 48
Ireland -> National University of Ireland Maynooth 2
Ireland -> Royal College of Surgeons in Ireland 2
Ireland -> Royal College of Surgeons in Ireland -> PubMed 2
Ireland -> TU Dublin 4
Ireland -> TU Dublin (Tallaght Campus) 7
Ireland -> TU Dublin (Tallaght Campus) -> PubMed 6
Ireland -> Teagasc 1

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