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Leonie S Young

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Medicine & Nursing

Details
Publications 42
As first author 0
As last author 27
Unique topics 454
Collaborations 47
Patents 2
Sources 8
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2017
2016
2015
2014
2013
2012
2011
2010
2009
Earlier
All
2017
2016
2015
2014
2013
2012
2011
2010
2009
Earlier

2017

Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings.
2017

Epigenome-wide SRC-1 mediated gene silencing represses cellular differentiation in advanced breast cancer.
2017

S100β as a serum marker in endocrine resistant breast cancer.
2016

Adaptation to AI therapy in breast cancer can induce dynamic alterations in ER activity resulting in estrogen independent metastatic tumours.
2016

Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases.
2016

Patient-Derived Xenografts of Breast Cancer.
2016

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.
2016

S100β as a serum marker in endocrine resistant breast cancer.
2015

CD44 increases the efficiency of distant metastasis of breast cancer.
2015

FKBPL: a marker of good prognosis in breast cancer.
2015

Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer.
2014

CD44 increases the efficiency of distant metastasis of breast cancer.
2014

Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells.
2014

Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis.
2014

NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis.
2014

Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy.
2013

ADAM22 as a Prognostic and Therapeutic Drug Target in the Treatment of Endocrine-Resistant Breast Cancer.
2013

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
2013

Growth factor receptor/steroid receptor cross talk in trastuzumab-treated breast cancer.
2012

AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells.
2012

Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling.
2012

Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling.
2012

The function of steroid receptor coactivator-1 in normal tissues and cancer.
2011

Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.
2011

Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer.
2011

HOXC11-SRC-1 regulation of S100beta in cutaneous melanoma: new targets for the kinase inhibitor dasatinib.
2011

Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1.
2011

RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.
2010

Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.
2010

Interaction of developmental transcription factor HOXC11 with steroid receptor coactivator SRC-1 mediates resistance to endocrine therapy in breast cancer [corrected].
2009

Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence.
2009

Lapatinib: a competitor or companion to trastuzumab?
2009

The role of oestrogen receptor {alpha} in human thyroid cancer: contributions from coregulatory proteins and the tyrosine kinase receptor HER2.
2008

Cyclooxygenase-2 predicts adverse effects of tamoxifen: a possible mechanism of role for nuclear HER2 in breast cancer patients.
2007

Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer.
2006

Growth factor-dependent regulation of survivin by c-myc in human breast cancer.
2006

Tamoxifen-induced ER-alpha-SRC-3 interaction in HER2 positive human breast cancer; a possible mechanism for ER isoform specific recurrence.
2005

Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer.
2005

Coregulatory protein-orphan nuclear receptor interactions in the human adrenal cortex.
2004

COX inhibitors modulate bFGF-induced cell survival in MCF-7 breast cancer cells.
2004

Expression of the breast cancer metastasis suppressor gene, BRMS1, in human breast carcinoma: lack of correlation with metastasis to axillary lymph nodes.
2004

Modulation of steroidogenic enzymes by orphan nuclear transcriptional regulation may control diverse production of cortisol and androgens in the human adrenal.

These arethe8 unique sources for Leonie S Young's 42 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 2
Ireland -> Dublin City University -> PubMed 2
Ireland -> National University of Ireland Galway 1
Ireland -> National University of Ireland Galway -> PubMed 1
Ireland -> Royal College of Surgeons in Ireland 30
Ireland -> Royal College of Surgeons in Ireland -> PubMed 25
Ireland -> University College Dublin 9
Ireland -> University College Dublin -> PubMed 9
May 9, 2013

ADAM22 FOR USE AS A PROGNOSTIC VARIABLE, AND TARGET FOR THERAPY, OF A METASTATIC BREAST CANCER DISEASE
+
Dec 3, 2009

A METHOD OF ASSESSING CANCER STATUS IN A BREAST CANCER PATIENT
+

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