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Martin Clynes

Institution

Dublin City University

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Subjects

Biochemistry

Microbiology

Details
Publications 232
As first author 5
As last author 115
Unique topics 1126
Collaborations 145
Patents 7
FP7 1
Sources 14
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2019
2018
2017
2016
2015
2014
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2012
2011
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2019
2018
2017
2016
2015
2014
2013
2012
2011
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2019

Improved yield of rhEPO in CHO cells with synthetic 5′ UTR
2019

Improvements in single‐use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance
2019

Reinventing the Wheel: Synthetic Circular RNAs for Mammalian Cell Engineering.
2018

A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts.
2018

A proteomic profiling dataset of recombinant Chinese hamster ovary cells showing enhanced cellular growth following miR-378 depletion.
2018

Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines.
2018

Clonal variation in productivity and proteolytic clipping of an Fc-fusion protein in CHO cells: Proteomic analysis suggests a role for defective protein folding and the UPR.
2018

Continuous translation of circularized mRNA improves recombinant protein titer.
2018

Copper-induced non-monotonic dose response in Caco-2 cells.
2018

Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal hydrolase 14.
2018

Improved yield of rhEPO in CHO cells with synthetic 5' UTR.
2018

Improvements in single-use bioreactor film material composition leads to robust and reliable Chinese hamster ovary cell performance.
2018

Increased growth rate and productivity following stable depletion of miR-7 in a mAb producing CHO cell line causes an increase in proteins associated with the Akt pathway and ribosome biogenesis.
2018

Leaky Expression of the TET-On System Hinders Control of Endogenous miRNA Abundance.
2018

The Expression Pattern of the Phosphoproteome Is Significantly Changed During the Growth Phases of Recombinant CHO Cell Culture.
2018

Transcriptomic analysis of IgG4 Fc-fusion protein degradation in a panel of clonally-derived CHO cell lines using RNASeq.
2018

Unexpected fluctuations of trace element levels in cell culture medium in vitro: caveat emptor.
2017

A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer.
2017

Conditional Knockdown of Endogenous MicroRNAs in CHO Cells Using TET-ON-SanDI Sponge Vectors.
2017

Differential Phosphoproteomic Analysis of Recombinant Chinese Hamster Ovary Cells Following Temperature Shift.
2017

Filter-Aided Sample Preparation (FASP) for Improved Proteome Analysis of Recombinant Chinese Hamster Ovary Cells.
2017

Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease.
2017

Novel panel of protein biomarkers to predict response to bortezomib-containing induction regimens in multiple myeloma patients.
2017

Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine.
2017

Phosphopeptide Enrichment and LC-MS/MS Analysis to Study the Phosphoproteome of Recombinant Chinese Hamster Ovary Cells.
2017

Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry
2017

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation.
2017

miR-CATCH Identifies Biologically Active miRNA Regulators of the Pro-Survival Gene XIAP, in Chinese Hamster Ovary Cells.
2016

Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics.
2016

Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry.
2016

Proteomic strategies in the search for novel pancreatic cancer biomarkers and drug targets: recent advances and clinical impact.
2016

Quantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome.
2016

The iron-responsive microsomal proteome of Aspergillus fumigatus
2016

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation.
2016

Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells.
2015

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression.
2015

Clinical utility of C-terminal telopeptide of type 1 collagen in multiple myeloma.
2015

Elevated 12-hydroxyeicosatetraenoic acid (12-HETE) levels in serum of individuals with newly diagnosed Type 1 diabetes.
2015

Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism.
2015

Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection
2015

Proteomic differences in recombinant CHO cells producing two similar antibody fragments.
2015

Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype.
2015

The iron-responsive microsomal proteome of Aspergillus fumigatus.
2015

Towards next generation CHO cell biology: Bioinformatics methods for RNA-Seq-based expression profiling.
2014

7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells.
2014

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.
2014

Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer.
2014

Bone disease in multiple myeloma: pathophysiology and management.
2014

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression.
2014

Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression.
2014

Conserved microRNA function as a basis for Chinese hamster ovary cell engineering.
2014

Elevated levels of 14-3-3 proteins, serotonin, gamma enolase and pyruvate kinase identified in clinical samples from patients diagnosed with colorectal cancer.
2014

Exposure of a corneal epithelial cell line (hTCEpi) to Demodex-associated Bacillus proteins results in an inflammatory response.
2014

Glycosylation patterns of kidney proteins differ in rat diabetic nephropathy.
2014

Identification and functional validation of RAD23B as a potential protein in human breast cancer progression.
2014

Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry.
2014

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
2014

Predictive biomarkers for dasatinib treatment in melanoma
2014

Transferrin-bound proteins as potential biomarkers for advanced breast cancer patients.
2013

A gene expression profile indicative of early stage HER2 targeted therapy response.
2013

CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.
2013

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies.
2013

Increased outer arm and core fucose residues on the N-glycans of mutated alpha-1 antitrypsin protein from alpha-1 antitrypsin deficient individuals.
2013

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy.
2013

Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin
2013

Proteomics in uveal melanoma.
2012

A novel neutrophil derived inflammatory biomarker of pulmonary exacerbation in cystic fibrosis.
2012

Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer
2012

Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea
2012

Differential expression of fourteen proteins between uveal melanoma from patients who subsequently developed distant metastases versus those who did Not.
2012

EGFR and HER2 inhibition in pancreatic cancer.
2012

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines.
2012

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.
2012

MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.
2012

Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line
2012

Resistance to paclitaxel in a cisplatin-resistant ovarian cancer cell line is mediated by P-glycoprotein
2012

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias.
2012

Transcriptomic analysis of clonal growth rate variation during CHO cell line development.
2011

2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines
2011

A novel neutrophil derived inflammatory biomarker of pulmonary exacerbation in cystic fibrosis.
2011

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients
2011

Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer.
2011

Biochemical relapse following radical prostatectomy and miR-200a levels in prostate cancer.
2011

CGCDB: a web-based resource for the investigation of gene coexpression in CHO cell culture.
2011

Characterization and response of newly developed high-grade glioma cultures to the tyrosine kinase inhibitors, erlotinib, gefitinib and imatinib.
2011

Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of diseasespecific biomarkers
2011

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.
2011

Engineering CHO cell growth by stable manipulation of miRNA expression.
2011

Generation of lung cancer cell line variants by drug selection or cloning.
2011

Impact of miR-7 over-expression on the proteome of Chinese hamster ovary cells.
2011

Invasive markers identified by gene expression profiling in pancreatic cancer.
2011

Large scale microarray profiling and coexpression network analysis of CHO cells identifies transcriptional modules associated with growth and productivity.
2011

Microarray expression profiling identifies genes regulating sustained cell specific productivity (S-Qp) in CHO K1 production cell lines.
2011

Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line.
2011

RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation
2011

Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype.
2011

Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.
2010

2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines.
2010

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients.
2010

Challenges of drug resistance in the management of pancreatic cancer
2010

Conditioned media from cell lines: a complementary model to clinical specimens for the discovery of disease-specific biomarkers.
2010

Decreasing Txnip mRNA and protein levels in pancreatic MIN6 cells reduces reactive oxygen species and restores glucose regulated insulin secretion.
2010

Engineering CHO cell growth and recombinant protein productivity by overexpression of miR-7.
2010

Identification of microRNAs with a role in glucose stimulated insulin secretion by expression profiling of MIN6 cells.
2010

Imatinib and docetaxel in combination can effectively inhibit glioma invasion in an in vitro 3D invasion assay.
2010

Inhibition of IGF1R activity enhances response to trastuzumab in HER-2-positive breast cancer cells.
2010

MAGE-D4B is a novel marker of poor prognosis and potential therapeutic target involved in breast cancer tumorigenesis.
2010

Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis
2010

MicroRNAs: tiny targets for engineering CHO cell phenotypes?
2010

Microarray and proteomics expression profiling identifies several candidates, including the valosin-containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines.
2010

Modulation of P-gp expression by lapatinib.
2010

Predicting cell-specific productivity from CHO gene expression.
2010

Recent advances in clinical proteomics using mass spectrometry.
2009

Alterations in integrin expression modulates invasion of pancreatic cancer cells
2009

Development of a high-performance liquid chromatographic-mass spectrometric method for the determination of cellular levels of the tyrosine kinase inhibitors lapatinib and dasatinib.
2009

Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer.
2009

Expression of multidrug resistance markers ABCB1 (MDR-1/ Pgp) and ABCC1 (MRP-1) in renal cell carcinoma
2009

Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal carcinoma
2009

Identification of pancreatic cancer invasion-related proteins by proteomic analysis
2009

MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines.
2009

Proteomic analysis of multidrug-resistance mechanisms in adriamycin-resistant variants of DLKP, a squamous lung cancer cell line.
2009

TMEM25, REPS2 and Meis 1: favourable prognostic and predictive biomarkers for breast cancer.
2009

Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.
2009

α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8.
2008

Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells
2008

Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis.
2008

CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.
2008

Development of taxane resistance in a panel of human lung cancer cell lines
2008

Feasibility and relevance of global expression profiling of gene transcripts in serum from breast cancer patients using whole genome microarrays and quantitative RT-PCR.
2008

Identification of pancreatic cancer invasion-related proteins by proteomic analysis.
2008

Membrane and membrane-associated proteins involved in the aggressive phenotype displayed by highly invasive cancer cells.
2008

Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines.
2008

Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry
2008

Proteomic analysis of conditioned media from glucose responsive and glucose non-responsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction.
2008

Proteomic profiling of CHO cells with enhanced rhBMP-2 productivity following co-expression of PACEsol.
2007

2-D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins.
2007

A microarray approach to translational medicine in breast cancer: how representative are cell line models of clinical conditions?
2007

Detection of amplifiable mRNA extracellular to insulin-producing cells: potential for predicting beta cell mass and function.
2007

Differential protein expression following low temperature culture of suspension CHO-K1 cells.
2007

Directed differentiation of mouse embryonic stem cells into pancreatic-like or neuronal- and glial-like phenotypes.
2007

Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue.
2007

Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents.
2007

Identification of a novel, functional role for S100A13 in invasive lung cancer cell lines.
2007

Initial identification of low temperature and culture stage induction of miRNA expression in suspension CHO-K1 cells.
2007

Investigation of the role of p53 in chemotherapy resistance of lung cancer cell lines.
2007

Limbal stem cells, a review of their identification and culture for clinical use.
2007

MDR1/P-glycoprotein and MRP-1 drug efflux pumps in pancreatic carcinoma.
2007

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.
2007

Prevalence and prognostic and predictive relevance of PRAME in breast cancer.
2007

Proteomic analysis of isolated membrane fractions from superinvasive cancer cells
2007

Proteomic analysis to dissect mitoxantrone resistance-associated proteins in a squamous lung carcinoma.
2007

Proteomic approaches for serum biomarker discovery in cancer.
2007

Proteomic investigation of taxol and taxotere resistance and invasiveness in a squamous lung carcinoma cell line.
2007

Proteomic profiling of secreted proteins from CHO cells using Surface-Enhanced Laser desorption ionization time-of-flight mass spectrometry.
2007

Purification and identification of a 7.6-kDa protein in media conditioned by superinvasive cancer cells.
2007

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.
2007

Transcriptional profiling of gene expression changes in a PACE-transfected CHO DUKX cell line secreting high levels of rhBMP-2.
2006

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.
2006

Biomarkers and multiple drug resistance in breast cancer.
2006

Detecting de novo insulin synthesis in embryonic stem cell-derived populations.
2006

Gene Expression Microarray Technology: Some Applications in Lung Cancer Research.
2006

Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays.
2006

Low adhesiveness coupled with high superinvasiveness in vitro predicts the in vivo metastatic potential of a mouse mammary adenocarcinoma cell line.
2006

Phenotypic and global gene expression profile changes between low passage and high passage MIN-6 cells.
2006

Pre-exposure to yeast protects larvae of Galleria mellonellafrom a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides
2006

Proliferation control strategies to improve productivity and survival during CHO based production culture : A summary of recent methods employed and the effects of proliferation control in product secreting CHO cell lines.
2006

Proteomic analysis of isolated membrane fractions from superinvasive cancer cells.
2006

Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress.
2006

RNA Interference with siRNA.
2006

Rapid and sensitive liquid chromatography-tandem mass spectrometry for the quantitation of epirubicin and identification of metabolites in biological samples.
2006

The role of recombinant proteins in the development of serum-free media.
2005

Evaluation of recombinant human transferrin (DeltaFerrin(TM)) as an iron chelator in serum-free media for mammalian cell culture.
2005

Molecular markers of multiple drug resistance in breast cancer.
2005

Monoclonal antibody 5C3 raised against formalin fixed paraffin-embedded invasive breast tumour tissue: characterisation of its reactive antigen via immunoprecipitation and internal sequencing.
2005

Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides.
2004

A new superinvasive in vitro phenotype induced by selection of human breast carcinoma cells with the chemotherapeutic drugs paclitaxel and doxorubicin.
2004

Construction and transfection of a ribozyme targeting human caspase-3.
2004

Detection of Specific mRNAs in Culture Medium Conditioned by Human Tumour Cells: Potential for New Class of Cancer Biomarkers in Serum.
2004

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.
2004

Expression and prognostic relevance of Mcl-1 in breast cancer.
2004

Expression in murine teratocarcinoma F9 cells of transcription factors involved in pancreas development.
2004

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.
2004

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes
2004

Investigation of MRP-1 protein and MDR-1 P-glycoprotein expression in invasive breast cancer: a prognostic study.
2004

Mechanisms associated with loss of glucose responsiveness in beta cells.
2004

Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells.
2004

Two-deoxyglucose as an anti-metabolite in human carcinoma cell line RPMI-2650 and drug-resistant variants.
2003

Challenges in molecular analysis for individualized cancer therapy.
2003

Characterisation of BHK-21 cells engineered to secrete human insulin.
2003

Galectin-3 expression alters adhesion, motility and invasion in a lung cell line (DLKP), in vitro.
2003

Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines.
2003

Lack of prognostic significance of survivin, survivin-deltaEx3, survivin-2B, galectin-3, bag-1, bax-alpha and MRP-1 mRNAs in breast cancer.
2003

Survivin: role in normal cells and in pathological conditions.
2002

Engineering Vero cells to secrete human insulin.
2002

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.
2002

Structure-activity relationship of indomethacin analogues for MRP-1, COX-1 and COX-2 inhibition. identification of novel chemotherapeutic drug resistance modulators.
2001

Bromodeoxyuridine increases keratin 19 protein expression at a posttranscriptional level in two human lung tumor cell lines.
2001

Bromodeoxyuridine induces integrin expression at transcriptional (alpha2 subunit) and post-transcriptional (beta1 subunit) levels, and alters the adhesive properties of two human lung tumour cell lines.
2001

Selection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness.
2001

Synthesis of indomethacin analogues for evaluation as modulators of MRP activity.
2000

Altered cell cycle response of drug-resistant lung carcinoma cells to doxorubicin.
1999

A new monoclonal antibody that specifically recognises the MDR-3-encoded gene product.
1999

Altered expression of mRNAs for apoptosis-modulating proteins in a low level multidrug resistant variant of a human lung carcinoma cell line that also expresses mdr1 mRNA.
1999

Bromodeoxyuridine induces keratin protein synthesis at a posttranscriptional level in human lung tumour cell lines.
1999

Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines
1999

Preliminary immunocytochemical studies of MDR-1 and MDR-3 Pgp expression in B-cell leukaemias.
1998

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
1998

Human lung carcinoma cell line DLKP contains 3 distinct subpopulations with different growth and attachment properties.
1998

Monoclonal antibodies raised to paraffin wax embedded archival tissue; feasibility study of their potential to detect novel antigenic markers.
1998

Recent developments in drug resistance and apoptosis research.
1998

Regulation of keratin and integrin gene expression in cancer and drug resistance.
1998

Use of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistance.
1997

A new mdr-1 encoded P-170 specific monoclonal antibody: (6/1C) on paraffin wax embedded tissue without pretreatment of sections.
1997

Co-expression of MDR-associated markers, including P-170, MRP and LRP and cytoskeletal proteins, in three resistant variants of the human ovarian carcinoma cell line, OAW42.
1997

Isolation from a human MDR lung cell line of multiple clonal subpopulations which exhibit significantly different drug resistance.
1997

Membrane changes associated with the early stages of apoptosis in HEp-2 cells decrease susceptibility to adherence by Candida albicans
1997

The multidrug-resistant human lung tumour cell line, DLKP-A10, expresses novel drug accumulation and sequestration systems.
1996

Absence of correlation between chemo- and radioresistance in a range of human tumour cell lines.
1996

mdr1 ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines.
1995

Multiple drug resistance in variants of a human lung cell line exposed to adriamycin and VP-16.
1995

Separation of growth-stimulating activity of BSA fraction V from the bulk of albumin using Heparin Sepharose Chromatography.
1993

Cellular models for multiple drug resistance in cancer.
1993

Comparison of 5 microplate colorimetric assays for in vitro cytotoxicity testing and cell proliferation assays.
1993

Human cell lines as models for multidrug resistance in solid tumours.
1993

Multiple drug resistance in the human ovarian carcinoma cell line OAW42-A.
1993

Production of autostimulatory growth factors by the human carcinoma line, RPMI 2650.
1993

The use of reverse transcriptase-polymerase chain reaction (RT-PCR) to investigate specific gene expression in multidrug-resistant cells.
1992

Multiple drug-resistance in variant of a human non-small cell lung carcinoma cell line, DLKP-A.
1992

Preliminary studies of a monoclonal antibody raised to the over expressed plasma membrane associated glycoprotein of a multidrug resistant cell line.
1991

Factors influencing protease levels in animal cells in vitro.
1990

Cytological differences between normal and malignant human cell populations in culture.
1990

Establishment of two new multi-drug resistant variants of the human tumor line Hep-2.

These arethe14 unique sources for Martin Clynes's 232 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 195
Ireland -> Dublin City University -> PubMed 187
Ireland -> Maynooth University 37
Ireland -> Maynooth University -> PubMed 2
Ireland -> Royal College of Surgeons in Ireland 6
Ireland -> Royal College of Surgeons in Ireland -> PubMed 3
Ireland -> TU Dublin (Tallaght Campus) 1
Ireland -> TU Dublin (Tallaght Campus) -> PubMed 1
Ireland -> Trinity College Dublin 34
Ireland -> Trinity College Dublin -> PubMed 2
Ireland -> University College Cork 1
Ireland -> University College Cork -> PubMed 1
Ireland -> University College Dublin 2
Ireland -> University of Limerick 1
Aug 11, 2015

A method for monitoring response to therapy and recurrence of breast cancer
+
Sep 10, 2009

DETECTION AND TREATMENT OF AN INVASIVE CANCER PHENOTYPE
+
Mar 19, 2009

A METHOD OF ASSESSING CANCER STATUS IN AN INDIVIDUAL
+
Jan 29, 2009

MARKERS FOR INVASION IN BREAST AND LUNG CARCINOMA
+
Dec 24, 2008

DIFFERENTIAL EXPRESSION PROFILING ANALYSIS OF CELL CULTURE PHENOTYPES AND USES THEREOF
+
Nov 6, 2008

DIAGNOSTIC, PROGNOSTIC AND/OR PREDICTIVE INDICATORS OF BREAST CANCER
+
Mar 20, 2008

Differential expression profiling analysis of cell culture phenotypes and the uses thereof
+
Jul 1, 2010(FP7)

Active wound dressings based on biological mimicry
+

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