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Marian M Humphries

Institution

Trinity College Dublin

Contact

Subjects

Biochemistry

Microbiology

Details
Publications 43
As first author 3
As last author 2
Unique topics 302
Collaborations 42
Patents 1
Sources 6
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Earlier

2017

Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.
2017

Enhancement of outflow facility in the murine eye by targeting selected tight-junctions of Schlemm's canal endothelia
2017

Toward an elucidation of the molecular genetics of inherited retinal degenerations
2016

Blood-Brain Barrier Dysfunction as a Hallmark Pathology in Chronic Traumatic Encephalopathy.
2016

Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.
2015

Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier.
2014

Activation of Bax in three models of retinitis pigmentosa.
2014

Antioxidant therapy for retinal disease.
2014

Current therapeutic strategies for P23H RHO-linked RP.
2014

IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration.
2014

Inflammation in age-related macular degeneration.
2011

C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa.
2011

Calpain and photoreceptor apoptosis.
2011

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components.
2011

On further development of barrier modulation as a technique for systemic ocular drug delivery.
2011

Protein misfolding and potential therapeutic treatments in inherited retinopathies.
2011

Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa
2011

Systemic low-molecular weight drug delivery to pre-selected neuronal regions
2011

Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury.
2010

Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90)
2010

Protection of photoreceptors in a mouse model of RP10.
2010

Reversible and size-selective opening of the inner Blood-Retina barrier: a novel therapeutic strategy.
2010

Systemic low-molecular weight drug delivery to pre-selected neuronal regions.
2010

The pathophysiology of cigarette smoking and age-related macular degeneration.
2009

Adeno-associated virus-mediated rhodopsin replacement provides therapeutic benefit in mice with a targeted disruption of the rhodopsin gene.
2009

An experimental platform for systemic drug delivery to the retina
2009

Improved retinal function in a mouse model of dominant retinitis pigmentosa following AAV-delivered gene therapy.
2008

Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10).
2007

A transgenic mouse model for gene therapy of rhodopsin-linked Retinitis Pigmentosa.
2007

Altered expression and interaction of adherens junction proteins in the developing OLM of the Rho(-/-) mouse.
2007

RNA interference-mediated suppression and replacement of human rhodopsin in vivo.
2005

Aberrant retinal tight junction and adherens junction protein expression in an animal model of autosomal dominant Retinitis pigmentosa: the Rho(-/-) mouse.
2004

On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
2002

Murine model of autosomal dominant retinitis pigmentosa generated by targeted deletion at codon 307 of the rds-peripherin gene
1999

Retinitis pigmentosa and progressive sensorineural hearing loss caused by a C12258A mutation in the mitochondrial MTTS2 gene.
1996

Three keratin gene mutations account for the majority of dominant simplex epidermolysis bullosa cases within the population of Ireland.
1992

Autosomal dominant retinitis pigmentosa: a novel mutation at the peripherin/RDS locus in the original 6p-linked pedigree.
1992

Autosomal dominant retinitis pigmentosa: a novel mutation in the rhodopsin gene in the original 3q linked family.
1991

A three-base-pair deletion in the peripherin-RDS gene in one form of retinitis pigmentosa.
1991

Autosomal dominant retinitis pigmentosa: localization of a disease gene (RP6) to the short arm of chromosome 6.
1990

Autosomal dominant retinitis pigmentosa: linkage to rhodopsin and evidence for genetic heterogeneity.
1989

Autosomal dominant retinitis pigmentosa (ADRP): localization of an ADRP gene to the long arm of chromosome 3.
1989

Autosomal dominant retinitis pigmentosa: exclusion of a gene from extensive regions of chromosomes 6, 13, 20, and 21.

These arethe6 unique sources for Marian M Humphries's 43 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Royal College of Surgeons in Ireland 1
Ireland -> Royal College of Surgeons in Ireland -> PubMed 1
Ireland -> Trinity College Dublin 40
Ireland -> Trinity College Dublin -> PubMed 31
Ireland -> University College Dublin 2
Ireland -> University College Dublin -> PubMed 2
Mar 18, 2010

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