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Malachy McCann

Institution

Maynooth University

Contact

Subjects

Chemistry

Microbiology

Details
Publications 76
As first author 7
As last author 4
Unique topics 319
Collaborations 42
Patents 1
Sources 9
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All
2020
2019
2018
2017
2016
2015
2014
2013
2012
Earlier
All
2020
2019
2018
2017
2016
2015
2014
2013
2012
Earlier

2020

In Vivo Activity of Copper(II), Manganese(II), and Silver(I) 1,10-Phenanthroline Chelates
2019

(
2019

(E)-6,6'-(Diazene-1,2-di-yl)bis-(1,10-phenanthrolin-5-ol) tri-chloro-methane disolvate: a superconjugated ligand
2019

Disarming Pseudomonas aeruginosa Virulence by the Inhibitory Action of 1,10-Phenanthroline-5,6-Dione- Based Compounds: Elastase B (LasB) as a Chemotherapeutic Target
2018

In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes
2018

Unprecedented
2018

Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10- Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs
2018

Unprecedented in Vitro Antitubercular Activity of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs
2017

1,10-Phenanthroline-5,6-Dione-based Compounds are Effective in Disturbing Crucial Physiological Events of Phialophora Verrucosa
2017

Antifungal Potential of Copper(II), Manganese(II) and Silver(I) 1,10-Phenanthroline Chelates Against Multidrug-Resistant Fungal Species Forming the Candida haemulonii Complex: Impact on the Planktonic and Biofilm Lifestyles.
2017

In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes.
2017

Targeting the folate receptor: improving efficacy in inorganic medicinal chemistry.
2017

The Antibacterial Activity of Metal Complexes Containing 1, 10-phenanthroline: Potential as Alternatire Therapeutics in the Era of Antibiotic Resistance
2016

1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective in Disturbing Crucial Physiological Events of Phialophora verrucosa.
2016

The antibacterial activity of metal complexes containing 1,10-phenanthroline: Potential as alternative therapeutics in the era of antibiotic resistance.
2015

Anti-Pseudomonas aeruginosa activity of 1,10-phenanthroline-based drugs against both planktonic- and biofilm-growing cells.
2015

Tuberculosis: An Inorganic Medicinal Chemistry Perspective.
2015

Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity.
2014

Copper phenanthrene oxidative chemical nucleases.
2013

A new phenanthroline-oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction.
2013

Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities
2013

Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I)
2013

Regulating bioactivity of Cu2+ bis-1,10-phenanthroline artificial metallonucleases with sterically functionalized pendant carboxylates.
2013

Synthesis, structure and biological activity of silver(I) complexes of substituted imidazoles
2012

Exposure of Staphylococcus aureus to silver(I) induces a short term protective response.
2012

In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes
2012

Metal-based antimicrobial protease inhibitors.
2012

Potent oxidative DNA cleavage by the di-copper cytotoxin: [Cu2(μ-terephthalate)(1,10-phen)4]2+.
2012

Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I).
2012

Silver(I) complexes of 9-anthracenecarboxylic acid and imidazoles: synthesis, structure and antimicrobial activity
2011

DNA cleavage reactions of the dinuclear chemotherapeutic agent copper(II) bis-1,10- phenanthroline terephthalate.
2011

Molecular structure and spectroscopic studies on novel complexes of coumarin-3-carboxylic acid with Ni(II), Co(II), Zn(II) and Mn(II) ions based on density functional theory.
2011

Radical-induced DNA damage by cytotoxic square-planar copper(II) complexes incorporating o-phthalate and 1,10-phenanthroline or 2,2'-dipyridyl.
2011

Water-soluble CuII and MnII bis-phenanthroline octanedioate complexes with unprecedented nano and picomolar in vitro cytotoxicity as promising leads for chemotherapeutic drug development
2011

Water-soluble bis(1,10-phenanthroline) Octanedioate Cu2+ and Mn2+ Complexes with Unprecedented Nano and Picomolar in Vitro Cytotoxicity: Promising Leads for Chemotherapeutic Drug Development
2010

Analysis of the response of Candida albicans cells to Silver(I).
2010

Bis-phenanthroline copper(II) phthalate complexes are potent in vitro antitumour agents with 'self-activating' metallo-nuclease and DNA binding properties.
2010

Hexakis(prop-2-enamide)copper(II) bis(perchlorate) and hexakis(prop-2- enamide)manganese(II) bis(perchlorate)
2009

Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity.
2009

Exposure to caspofungin activates Cap and Hog pathways in Candida albicans.
2009

Is the C=O frequency shift a reliable indicator of coumarin binding to metal ions through the carbonyl oxygen?
2009

Role of cell cycle events and apoptosis in mediating the anti-cancer activity of a silver(I) complex of 4-hydroxy-3-nitro-coumarin-bis(phenanthroline) in human malignant cancer cells.
2009

Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]
2008

Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3].
2007

In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)] Æ 2H2O, [Cu(phen)2(mal)] Æ 2H2O and [Mn(phen)2(mal)] Æ 2H2O (malH2 = malonic acid) using human cancer cells.
2007

Mechanism of action of coumarin and silver(I)- coumarin complexes against the pathogenic yeast Candida albicans
2007

Synthesis and structure of metal complexes containing zwitterionic N-hydroxyimidazole ligands
2007

Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2] · 8.8H2O and [Cu(4-Mecdoa)(phen)2] · 13H2O (phen = 1,10-phenanthroline)
2007

[Ag2(aca)2]n and [Ag4(aca)4(NH3)2] (acaH = 9-anthracenecarboxylic acid): Synthesis, X-ray crystal structures, antimicrobial and anti-cancer activities
2006

'Silver bullets' in antimicrobial chemotherapy: Synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes
2006

A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells.
2006

In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines.
2006

In vitro anti-tumour effect of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)3](ClO4)2.4H2O and [Ag(phendione)2]ClO4 using human epithelial cell lines.
2006

In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)]x2H2O, [Cu(phen)2(mal)]x2H2O and [Mn(phen)2(mal)]x2H2O (malH2=malonic acid) using human cancer cells.
2006

Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans.
2006

Synthesis, Superoxide DismutaseMimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH2) and 3,3-Dimethylpentanedioic acid(3dmepdaH2): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)]2 · 6H2Oand [Cu(2dmepda)(bipy)(EtOH)]2 · 4EtOH (bipy = 2,2'Bipyridine)
2006

Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.
2006

Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenanthroline).
2006

Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(1) complexes
2006

Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes
2005

Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc)2(H2O)2] Æ 2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)
2005

Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine).
2004

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes
2004

Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to Amphotericin B and Miconazole
2004

Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells.
2004

Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2(NH3)2(salH)2] (salH2 ¼salicylic acid)
2004

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(40-thiazolyl)benzimidazole{thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl • H2O • EtOH and TBZH2NO3 (TBZH¼thiabendazole)
2004

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4’-thiazolyl)benzimazole {thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH = thiabendazole)
2004

Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands
2003

Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes.
2003

Synthesis and antimicrobial activity of (Z)-3-(1H-imidazol-1-yl)-2-phenylpropenenitrile and its metal complexes: X-ray crystal structures of the Zn(II) and Ag(I) complexes.
2003

Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole).
2001

Mixtures obtained by reacting trans-(�)-1,2diaminocyclohexane with acetylacetone in the presence of simple cobalt(II) salts.
2000

Synthesis and Biological Activity of Manganese (II) Complexes of Phthalic and Isophthalic Acid: X-Ray Crystal Structures of [Mn(ph)(Phen)(2)(H(2)O)]. 4H(2)O, [Mn(Phen)(2)(H(2)O)(2)](2)(Isoph)(2)(Phen). 12H(2)O and {[Mn(Isoph)(bipy)](4). 2.75biby}(n)(phH(2) = Phthalic Acid; isoph = Isophthalic Acid; phen = 1,10-Phenanthroline; bipy = 2,2-Bipyridine).
2000

Synthesis and antimicrobial activity of copper(II) and manganese(II) alpha,omega-dicarboxylate complexes.
1995

Synthesis and catalase activity of manganese (ii) complexes of cis-5-norbornene-endo-2, 3-dicarboxylic acid (ndaH2): x-ray crystal structure of [Mn(qb11-nda)(phen)2]• EtOH'H20 (phen = 1,10-phenanthroline)

These arethe9 unique sources for Malachy McCann's 76 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 9
Ireland -> Dublin City University -> PubMed 9
Ireland -> Dublin Institute of Technology 14
Ireland -> Dublin Institute of Technology -> PubMed 11
Ireland -> Maynooth University 44
Ireland -> Maynooth University -> PubMed 10
Ireland -> TU Dublin 9
Ireland -> TU Dublin (Tallaght Campus) 8
Ireland -> TU Dublin (Tallaght Campus) -> PubMed 7
May 22, 1996

NOVEL MN(II) CARBOXYLATE COMPLEXES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS DISPROPORTIONATION CATALYSTS
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