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Niamh Moran

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Details
Publications 50
As first author 2
As last author 16
Unique topics 394
Collaborations 55
Patents 3
Sources 9
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All
2017
2016
2015
2014
2013
2012
2011
2010
2009
Earlier
All
2017
2016
2015
2014
2013
2012
2011
2010
2009
Earlier

2017

Assessment of 'on-treatment platelet reactivity' and relationship with cerebral micro-embolic signals in asymptomatic and symptomatic carotid stenosis.
2017

Fibrinogen Motif Discriminates Platelet and Cell Capture in Peptide-Modified Gold Micropore Arrays.
2017

The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance.
2016

Peptide-Mediated Platelet Capture at Gold Micropore Arrays.
2015

The lateral diffusion and fibrinogen induced clustering of platelet integrin αIIbβ3 reconstituted into physiologically mimetic GUVs.
2015

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.
2015

Virtual screening using combinatorial cyclic Peptide libraries reveals protein interfaces readily targetable by cyclic peptides.
2014

Cadherin juxtamembrane region derived peptides inhibit TGFβ1 induced gene expression.
2014

Discovering Anti-platelet Drug Combinations with an Integrated Model of Activator-Inhibitor Relationships, Activator-Activator Synergies and Inhibitor-Inhibitor Synergies.
2014

Increased thrombin generation potential in symptomatic versus asymptomatic moderate or severe carotid stenosis and relationship with cerebral microemboli.
2014

Poly(Ethylene glycol)-based backbones with high peptide loading capacities.
2014

Poly(Ethylene glycol)-based backbones with high peptide loading capacities.
2014

RGD labeled Ru(II) polypyridyl conjugates for platelet integrin αIIbβ3 recognition and as reporters of integrin conformation.
2013

A platelet dense-granule secretion defect may lead to a muted inflammatory cell mobilization response in Cystic Fibrosis patients.
2013

Increased platelet counts and platelet activation in early symptomatic versus asymptomatic carotid stenosis and relationship with microembolic status: Results from the Platelets And Carotid Stenosis (PACS) Study
2013

Pregnancy-Specific Glycoproteins Bind Integrin αIIbβ3 and Inhibit the Platelet-Fibrinogen Interaction.
2013

Pregnancy-specific glycoproteins bind integrin alpha IIb beta 3 and inhibit the platelet-fibrinogen interaction
2013

Regulation of platelet activity in a changing redox environment.
2012

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.
2012

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase a oncogene.
2011

Platelet signalling networks: pathway perturbation demonstrates differential sensitivity of ADP secretion and fibrinogen binding.
2011

Platelet signalling networks: pathways perturbation demonstrates differential sensitivity of ADP secretion and fibinogen binding.
2011

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.
2010

Integrin α(IIb)β₃ exists in an activated state in subjects with elevated plasma homocysteine levels.
2010

Integrins as therapeutic targets: lessons and opportunities.
2010

Integrins as therapeutic targets: lessons and opportunities.
2010

Protein interactions with the platelet integrin alpha(IIb) regulatory motif.
2009

Electrochemical desorption of fibrinogen from gold.
2009

Ligand switching in cell-permeable peptides: manipulation of the alpha-integrin signature motif.
2008

Compartmentalization regulates the interaction between the platelet integrin alpha IIb beta 3 and ICln.
2008

RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin alpha(IIb)beta3.
2008

Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging
2007

A peptide affinity column for the identification of integrin alpha IIb-binding proteins.
2007

S-Nitrosylation of platelet alphaIIbbeta3 as revealed by Raman spectroscopy.
2006

A novel functional role for the highly conserved alpha-subunit KVGFFKR motif distinct from integrin alphaIIbbeta3 activation processes.
2006

Absolute net charge and the biological activity of oligopeptides.
2006

Bacitracin reveals a role for multiple thiol isomerases in platelet function.
2006

Bioinformatic discovery of novel bioactive peptides.
2006

Monitoring modulators of platelet aggregation in a microtiter plate assay.
2004

Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.
2004

ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation.
2004

Novel integrin-specific targets for anti-platelet therapies.
2004

Redox modulation of integrin [correction of integin] alpha IIb beta 3 involves a novel allosteric regulation of its thiol isomerase activity.
2003

A palmitylated peptide derived from the glycoprotein Ib beta cytoplasmic tail inhibits platelet activation.
2002

A novel hemizygous Bernard-Soulier Syndrome (BSS) mutation in the amino terminal domain of glycoprotein (GP)Ibbeta--platelet characterization and transfection studies.
2001

A Val193Met mutation in GPIIIa results in a GPIIb/IIIa receptor with a constitutively high affinity for a small ligand.
2000

Surface expression of glycoprotein ib alpha is dependent on glycoprotein ib beta: evidence from a novel mutation causing Bernard-Soulier syndrome.
2000

The platelet integrin alpha IIbbeta 3 has an endogenous thiol isomerase activity.
1998

A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis.
1997

Continued thromboxane A2 formation despite administration of a platelet glycoprotein IIb/IIIa antagonist in patients undergoing coronary angioplasty.

These arethe9 unique sources for Niamh Moran's 50 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 6
Ireland -> Dublin City University -> PubMed 5
Ireland -> Royal College of Surgeons in Ireland 40
Ireland -> Royal College of Surgeons in Ireland -> PubMed 34
Ireland -> University College Cork 2
Ireland -> University College Cork -> PubMed 1
Ireland -> University College Dublin 4
Ireland -> University College Dublin -> PubMed 2
Ireland -> University of Limerick 1
Jun 24, 2009

IMAGING DYES AND USE THEREOF
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Mar 2, 2006

BIOACTTVE PEPTIDES
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Nov 18, 2004

INHIBITION OF PLATELET AGGREGATION THROUGH ACYCLOVIR AND TWO PEPTIDE ANTAGONISTS
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