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Robert O'Connor

Institution

Dublin City University

Contact

Subjects

Microbiology

Biochemistry

Details
Publications 74
As first author 18
As last author 19
Unique topics 585
Collaborations 113
Sources 12
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2020
2019
2018
2017
2016
2015
2013
2012
2011
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2020
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2012
2011
Earlier

2020

Tuning of oxygen vacancy-induced electrical conductivity in Ti-doped hematite films and its impact on photoelectrochemical water splitting
2019

Dasatinib Treatment Increases Sensitivity to c-Met Inhibition in Triple-Negative Breast Cancer Cells.
2019

Hard X-ray photoelectron spectroscopy study of copper formation by metal salt inclusion in a polymer film
2019

Surface characterization of Poly 2-Vinylpyridine - a polymer for area selective deposition techniques
2018

Characterisation of electroless deposited Cobalt by hard and soft X-ray photoemission spectroscopy
2018

Nitrogen reactive ion etch processes for the selective removal of poly-(4-vinylpyridine) in block copolymer films.
2017

Adherence to COPD management guidelines in general practice? A review of the literature.
2017

Hidradenitis Suppurativa and Crohn's Disease: A Case Series.
2017

Interventions to Improve the Treatment of Malaria in an Acute Teaching Hospital in Ireland.
2016

Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models.
2016

Drug-induced photodistributed rash.
2016

Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models.
2016

Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles.
2016

In-situ surface and interface study of atomic oxygen modified carbon containing porous low-κ dielectric films for barrier layer applications
2015

Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model.
2015

Data supporting the shedding of larger extracellular vesicles by multidrug resistant tumour cells.
2015

Multidrug resistant tumour cells shed more microvesicle-like EVs and less exosomes than their drug-sensitive counterpart cells.
2015

Using electronic medical records to determine prevalence and treatment of mental disorders in primary care: a database study
2013

A gene expression profile indicative of early stage HER2 targeted therapy response.
2013

HRG-1 enhances cancer cell invasive potential and couples glucose metabolism to cytosolic/extracellular pH gradient regulation by the vacuolar-H(+) ATPase.
2013

Youth mental health in deprived urban areas: a Delphi study on the role of the GP in early intervention.
2012

An evidence-based assessment of primary care needs in an economically deprived Urban community.
2012

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines.
2012

Stable Aqueous Dispersions of Glycopeptide-Grafted Selectably Functionalized Magnetic Nanoparticles.
2012

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias.
2012

The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines
2011

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients
2011

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines
2011

Comparative bioenergetic assessment of transformed cells using a cell energy budget platform.
2011

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.
2011

Simultaneous determination of efavirenz, rifampicin and its metabolite desacetyl rifampicin levels in human plasma.
2010

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients.
2010

Artificial neural networks for classification in metabolomic studies of whole cells using 1H nuclear magnetic resonance.
2010

Challenges of drug resistance in the management of pancreatic cancer
2010

Degradation and breakdown characteristics of thin MgO dielectric layers
2010

Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells.
2010

Modulation of P-gp expression by lapatinib.
2010

Safety implications of the Boyle-Davis mouth gag and tracheal tube position in tonsillectomy.
2010

Simultaneous determination of anthracyclines and taxanes in human serum using online sample extraction coupled to high performance liquid chromatography with UV detection.
2010

Time dependent dielectric breakdown and stress induced leakage current characteristics of 8Å EOT HfO2 N-MOSFETS
2009

A review of mechanisms of circumvention and modulation of chemotherapeutic drug resistance.
2009

Development of a high-performance liquid chromatographic-mass spectrometric method for the determination of cellular levels of the tyrosine kinase inhibitors lapatinib and dasatinib.
2009

Evaluation of waist-mounted tri-axial accelerometer based fall-detection algorithms during scripted and continuous unscripted activities.
2009

Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.
2008

CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.
2008

Metabolomic studies of human lung carcinoma cell lines using in vitro (1)H NMR of whole cells and cellular extracts.
2007

Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue.
2007

Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents.
2007

MDR1/P-glycoprotein and MRP-1 drug efflux pumps in pancreatic carcinoma.
2007

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.
2007

The pharmacology of cancer resistance.
2006

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.
2006

Rapid and sensitive liquid chromatography-tandem mass spectrometry for the quantitation of epirubicin and identification of metabolites in biological samples.
2005

Electrical and chemical characterisation of ultrathin transistor gate dielectric layers
2004

A new superinvasive in vitro phenotype induced by selection of human breast carcinoma cells with the chemotherapeutic drugs paclitaxel and doxorubicin.
2004

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.
2004

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.
2004

Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes
2004

Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells.
2003

Challenges in molecular analysis for individualized cancer therapy.
2003

Erythroid hypoplasia associated with leptospirosis.
2002

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.
2002

Structure-activity relationship of indomethacin analogues for MRP-1, COX-1 and COX-2 inhibition. identification of novel chemotherapeutic drug resistance modulators.
2001

Synthesis of indomethacin analogues for evaluation as modulators of MRP activity.
2000

Regulation of survival signals from the insulin-like growth factor-I receptor.
2000

The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis.
1998

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
1998

Recent developments in drug resistance and apoptosis research.
1998

Survival factors and apoptosis.
1996

Determination of serum and tissue levels of phenazines including clofazimine.
1995

An investigation of the pharmacology of selected anti-mycobacterial phenazines
1995

The pharmacology, metabolism, and chemistry of clofazimine.
1995

Use of proton NMR spectroscopy in the toxicological evaluation of new anti-mycobacterial agents.
1976

The Place of the Research Assistant in the Organisation and Conduct of Research Projects

These arethe12 unique sources for Robert O'Connor's 74 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 48
Ireland -> Dublin City University -> PubMed 40
Ireland -> Maynooth University 5
Ireland -> Maynooth University -> PubMed 1
Ireland -> TU Dublin (Tallaght Campus) 2
Ireland -> TU Dublin (Tallaght Campus) -> PubMed 2
Ireland -> Trinity College Dublin 11
Ireland -> Trinity College Dublin -> PubMed 2
Ireland -> University College Cork 8
Ireland -> University College Cork -> PubMed 8
Ireland -> University of Limerick 7
Ireland -> University of Limerick -> PubMed 5

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