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R William G Watson

Institution

University College Dublin

Contact

Subjects

Biochemistry

Medicine & Nursing

Details
Publications 135
As first author 18
As last author 63
Unique topics 820
Collaborations 101
Sources 14
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2018
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2016
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2011
2010
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2018
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Earlier

2018

Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer.
2018

Role of serum response factor expression in prostate cancer biochemical recurrence.
2017

Advances in Precision Medicine: Tailoring Individualized Therapies.
2017

High dose statin prophylaxis in cardiopulmonary bypass related surgery: clinical utility.
2017

Investigating the role of the IGF axis as a predictor of biochemical recurrence in prostate cancer patients post-surgery.
2017

Predicting outcome: role of gene signatures.
2017

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation.
2016

Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential.
2016

Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo.
2016

Importance of fundamental science as the cornerstone for translational research.
2016

MARCKS promotes invasion and is associated with biochemical recurrence in prostate cancer.
2016

Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology.
2016

Serial cytokine alterations and abnormal neuroimaging in newborn infants with encephalopathy.
2016

Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer.
2016

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation.
2016

The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer.
2015

Commercialized biomarkers: new horizons in prostate cancer diagnostics.
2015

Cyclodextrin mediated delivery of NF-κB and SRF siRNA reduces the invasion potential of prostate cancer cells in vitro.
2015

Improving Multivariable Prostate Cancer Risk Assessment Using The Prostate Health Index.
2015

Persistent systemic monocyte and neutrophil activation in neonatal encephalopathy.
2015

Predicting prostate cancer: analysing the clinical efficacy of prostate cancer risk calculators in a referral population.
2015

Relationship between serum response factor and androgen receptor in prostate cancer.
2015

The ERSPC Risk Calculators Significantly Outperform The PCPT 2.0 In The Prediction Of Prostate Cancer; A Multi-Institutional Study.
2014

Neonatal brain injury and systemic inflammation: modulation by activated protein C ex vivo.
2014

Physical activity and its mechanistic effects on prostate cancer.
2014

Prostate cancer risk assessment tools in an unscreened population.
2014

The analysis of serum response factor expression in bone and soft tissue prostate cancer metastases
2013

Evaluation of prediction models for the staging of prostate cancer.
2013

The analysis of serum response factor expression in bone and soft tissue prostate cancer metastases.
2012

EuroSCORE and neutrophil adhesion molecules predict outcome post-cardiac surgery.
2012

Patented prostate cancer biomarkers.
2011

A hierarchy of distress and invariant item ordering in the General Health Questionnaire-12.
2011

Biomarker research in prostate cancer--towards utility, not futility.
2011

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines
2011

Epstein criteria for insignificant prostate cancer.
2010

A gender comparison of postobstructive injury in the rat kidney.
2010

Applying random forests to identify biomarker panels in serum 2D-DIGE data for the detection and staging of prostate cancer.
2010

Benefits of heat treatment to the protease packed neutrophil for proteome analysis: halting protein degradation.
2010

Detecting soluble clusterin in in-vitro and in-vivo models of prostate cancer.
2010

Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.
2010

Ensemble based system for whole-slide prostate cancer probability mapping using color texture features.
2010

Evaluation of Zinc-alpha-2-Glycoprotein and Proteasome Subunit beta-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology.
2010

Integrating biobanks: addressing the practical and ethical issues to deliver a valuable tool for cancer research.
2009

Carbonic anhydrase IX expression in prostate cancer.
2009

Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation.
2009

External validation of the 2007 and 2001 Partin tables in Irish prostate cancer patients.
2009

Generation of an epigenetic signature by chronic hypoxia in prostate cells.
2009

Hypoxia increases normal prostate epithelial cell resistance to receptor-mediated apoptosis via AKT activation.
2009

Neutrophil immunosurveillance for heart transplant rejection: a prospective study.
2009

Novel predictive tools for Irish radical prostatectomy pathological outcomes: development and validation.
2009

digeR: a graphical user interface R package for analyzing 2D-DIGE data.
2008

Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines.
2008

Exploring mechanisms involved in renal tubular sensing of mechanical stretch following ureteric obstruction.
2008

Statins alter neutrophil migration by modulating cellular Rho activity--a potential mechanism for statins-mediated pleotropic effects?
2008

The single insult of hypoxic preconditioning induces an antiapoptotic response in human proximal tubular cells, in vitro, across cold storage.
2008

Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease.
2007

Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells.
2007

Gender differences in the renin-angiotensin and nitric oxide systems: relevance in the normal and diseased kidney.
2007

In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer.
2007

Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis.
2007

Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms.
2007

Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo.
2006

Application of proteomic strategies to the identification of urinary biomarkers for prostate cancer: a review.
2006

Effects of the dual 5 alpha-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines.
2006

Expression and regulation of connective tissue growth factor by transforming growth factor beta and tumour necrosis factor alpha in fibroblasts isolated from strictures in patients with Crohn's disease.
2006

Heat shock-induced protection of renal proximal tubular epithelial cells from cold storage and rewarming injury.
2006

Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells.
2006

Urinary markers for prostate cancer.
2005

Delayed graft function: a dilemma in renal transplantation.
2005

Resistance to caspase-dependent, hypoxia-induced apoptosis is not hypoxia-inducible factor-1 alpha mediated in prostate carcinoma cells.
2005

Targeting apoptosis in prostate cancer: focus on caspases and inhibitors of apoptosis proteins.
2004

An antisense oligonucleotide to cIAP-1 sensitizes prostate cancer cells to fas and TNFalpha mediated apoptosis.
2004

Apigenin drives the production of reactive oxygen species and initiates a mitochondrial mediated cell death pathway in prostate epithelial cells.
2004

Caffeic acid phenethyl ester-induced PC-3 cell apoptosis is caspase-dependent and mediated through the loss of inhibitors of apoptosis proteins.
2004

Differentiation-induced HL-60 cell apoptosis: a mechanism independent of mitochondrial disruption?
2004

Future opportunities for the diagnosis and treatment of prostate cancer.
2004

Gene expression profile of inflammatory neutrophils: alterations in the inhibitors of apoptosis proteins during spontaneous and delayed apoptosis.
2004

Gene profiling of in vitro and in vivo models of delayed neutrophil apoptosis: a common pathway?
2004

Hypoxia inhibits human bladder smooth muscle cell proliferation: a potential mechanism of bladder dysfunction.
2004

Increased vascular endothelial growth factor production in fibroblasts isolated from strictures in patients with Crohn's disease.
2004

Labor promotes neonatal neutrophil survival and lipopolysaccharide responsiveness.
2004

Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro.
2004

Prostate epithelial cell differentiation and its relevance to the understanding of prostate cancer therapies.
2003

Apoptosis in the prostate.
2003

DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): modulation during epithelial-mesenchymal transition.
2003

Endothelin in unilateral ureteral obstruction: vascular and cellular effects.
2003

Heat shock proteins in the genitourinary system.
2003

Human nucleus pulposis can respond to a pro-inflammatory stimulus.
2003

Mechanical deformation induced apoptosis in human proximal renal tubular epithelial cells is caspase dependent.
2003

Phytoestrogens and prostate cancer.
2003

Polyunsaturated and monounsaturated fatty acids increase neutral lipid accumulation, caspase activation and apoptosis in a neutrophil-like, differentiated HL-60 cell line.
2003

Pressure effects on cellular systems: is there a link with benign prostatic hyperplasia?
2002

Androgen-mediated resistance to apoptosis.
2002

Cytoprotective effects of nitrates in a cellular model of hydronephrosis.
2002

Effects of cyclic stretch on prostatic cells in culture.
2002

Glucose, but not glutamine, protects against spontaneous and anti-Fas antibody-induced apoptosis in human neutrophils.
2002

Increased adhesion molecule expression in serosal fibroblasts isolated from patients with inflammatory bowel disease is secondary to inflammation.
2002

Inhibitors of apoptosis proteins in prostate cancer cell lines.
2002

Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators.
2002

Redox regulation of neutrophil apoptosis.
2002

The loss of IAP expression during HL-60 cell differentiation is caspase-independent.
2001

Caspase 3 expression in benign prostatic hyperplasia and prostate carcinoma.
2001

Insulin-like growth factor I and prostate cancer.
2001

Nitric oxide in unilateral ureteral obstruction: effect on regional renal blood flow.
2001

Priming prostate carcinoma cells for increased apoptosis is associated with up-regulation of the caspases.
2000

Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis.
2000

Defining a role for the inhibitors of apoptosis proteins in prostate cancer.
2000

Glutathione depletion-induced neutrophil apoptosis is caspase 3 dependent.
2000

Heat-shock proteins inhibit induction of prostate cancer cell apoptosis.
2000

Insulin-like growth factor-1 alters apoptotic signalling in prostate cancer.
2000

Neutrophil apoptosis is delayed in patients with inflammatory bowel disease.
2000

Signaling for the caspases: their role in prostate cell apoptosis.
2000

Target sites for manipulating apoptosis in prostate cancer.
2000

Thiol-mediated apoptosis in prostate carcinoma cells.
1999

A blueprint for Europe.
1999

Caspase protease manipulation: a novel approach to apoptotic induction in prostate cancer.
1999

International affairs. Irish nursing for the next millennium.
1999

Involvement of tyrosine protein kinase in IFN-gamma-induced human endothelial cell apoptosis.
1999

Regulation of Fas antibody induced neutrophil apoptosis is both caspase and mitochondrial dependent.
1998

Publishing the results of factor analysis: interpretation and presentation.
1997

Differential effects of lower limb revascularisation on organ injury and the role of the amino acid taurine.
1997

Induction of human endothelial cell apoptosis requires both heat shock and oxidative stress responses.
1997

Pre-operative neutrophil and monocyte activation state predicts post-operative neutrophil and monocyte function.
1996

Bacterial ingestion, tumor necrosis factor-alpha, and heat induce programmed cell death in activated neutrophils.
1996

Mechanisms involved in sodium arsenite-induced apoptosis of human neutrophils.
1996

Mechanisms involved in the induction of human endothelial cell necrosis.
1996

Neutrophils undergo apoptosis following ingestion of Escherichia coli.
1996

The beneficial effect of taurine on the prevention of human endothelial cell death.
1995

Exposure of the peritoneal cavity to air regulates early inflammatory responses to surgery in a murine model.
1995

Failure of macrophage activation in experimental obstructive jaundice: association with bacterial translocation.
1995

Induction of heat shock protein 72 prevents neutrophil-mediated human endothelial cell necrosis.
1995

Role of lipopolysaccharide and tumor necrosis factor-alpha in induction of hepatocyte necrosis.
1995

Role of nitric oxide in lung injury associated with experimental acute pancreatitis.
1994

Immune function in patients undergoing open vs laparoscopic cholecystectomy.
1994

Nitric oxide (endothelium-derived relaxing factor) attenuates revascularization-induced lung injury.

These arethe14 unique sources for R William G Watson's 135 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 5
Ireland -> Dublin City University -> PubMed 5
Ireland -> National University of Ireland Galway 1
Ireland -> National University of Ireland Galway -> PubMed 1
Ireland -> Royal College of Surgeons in Ireland 18
Ireland -> Royal College of Surgeons in Ireland -> PubMed 17
Ireland -> TU Dublin (Tallaght Campus) 2
Ireland -> TU Dublin (Tallaght Campus) -> PubMed 2
Ireland -> Trinity College Dublin 6
Ireland -> Trinity College Dublin -> PubMed 5
Ireland -> University College Cork 2
Ireland -> University College Cork -> PubMed 2
Ireland -> University College Dublin 101
Ireland -> University College Dublin -> PubMed 100

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