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Sinead Toomey

Institution

Royal College of Surgeons in Ireland

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Subjects

Biochemistry

Details
Publications 26
As first author 5
As last author 0
Unique topics 236
Collaborations 64
Sources 9
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2018
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2018

An insight into the molecular genetics of a uveal melanoma patient cohort.
2018

Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH).
2017

A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer.
2017

Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers.
2017

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.
2017

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.
2016

A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib.
2016

A stepwise integrated approach to personalized risk predictions in stage III colorectal cancer.
2016

BCL-2 system analysis identifies high-risk colorectal cancer patients.
2016

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.
2016

The impact of ERBB-family germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2-positive breast cancer.
2015

A preclinical evaluation of the PI3K alpha/delta dominant inhibitor BAY 80-6946 in HER2-positive breast cancer models with acquired resistance to the HER2-targeted therapies trastuzumab and lapatinib.
2015

HER2-family signalling mechanisms, clinical implications and targeting in breast cancer.
2015

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.
2014

A preclinical evaluation of the PI3K alpha/delta dominant inhibitor BAY 80-6946 in HER2-positive breast cancer models with acquired resistance to the HER2-targeted therapies trastuzumab and lapatinib.
2014

BCL2 protein signalling determines acute responses to neoadjuvant chemoradiotherapy in rectal cancer.
2014

HER2-family signalling mechanisms, clinical implications and targeting in breast cancer.
2011

Divergent effects of a CLA-enriched beef diet on metabolic health in ApoE(-/-) and ob/ob mice.
2011

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice.
2011

Transcriptomic coordination in the human metabolic network reveals links between n-3 fat intake, adipose tissue gene expression and metabolic health.
2010

Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome.
2010

The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA.
2009

Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome.
2003

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.
2003

Cyclooxygenase isoforms and platelet vessel wall interactions in the apolipoprotein E knockout mouse model of atherosclerosis.
2003

Regression of pre-established atherosclerosis in the apoE-/- mouse by conjugated linoleic acid.

These arethe9 unique sources for Sinead Toomey's 26 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 4
Ireland -> Dublin City University -> PubMed 4
Ireland -> National University of Ireland Galway 1
Ireland -> National University of Ireland Galway -> PubMed 1
Ireland -> Royal College of Surgeons in Ireland 15
Ireland -> Royal College of Surgeons in Ireland -> PubMed 11
Ireland -> Teagasc 1
Ireland -> University College Dublin 5
Ireland -> University College Dublin -> PubMed 5

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