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Aideen Long

Institution

Trinity College Dublin

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Subjects

Biochemistry

Details
Publications 71
As first author 14
As last author 21
Unique topics 487
Collaborations 77
Sources 9
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2020
2018
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2015
2014
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2012
2011
Earlier
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2020
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2012
2011
Earlier

2020

Western European Shelf Pelagic Acoustic Survey (WESPAS) 13 June - 24 July, 2019
2018

CD3?Expression defines functionally distinct subsets of V?1 T cells in patients with human immunodeficiency virus infection
2018

Identifying a Novel Role for Fractalkine (CX3CL1) in Memory CD8
2018

Identifying a Novel Role for Fractalkine (CX3CL1) in Memory CD8+ T Cell Accumulation in the Omentum of Obesity-Associated Cancer Patients.
2018

RAB40C regulates RACK1 stability via theubiquitin–proteasome system
2018

Western European Shelf Pelagic Acoustic Survey (WESPAS) 10 June – 24 July, 2018
2018

siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth
2017

Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin-??v trafficking
2017

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism
2016

A fluorescent analogue of tauroursodeoxycholic acid reduces ER stress and is cytoprotective.
2016

Roles for RACK1 in cancer cell migration and invasion.
2016

Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism.
2015

Candidate Gene Knockdown in Celiac Disease.
2015

Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion
2015

RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration.
2014

New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.
2014

Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration.
2014

Protein kinase C: a regulator of cytoskeleton remodelling and T-cell migration.
2014

The role of chemokines in acute and chronic hepatitis C infection.
2013

Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection.
2013

Hepatitis C Virus targets the Interferon-¿ JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes.
2013

New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid.
2013

Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease
2013

RACK(1) to the future - a historical perspective
2013

The role of chemokines in acute and chronic hepatitis C infection.
2012

Deoxycholic acid impairs glycosylation and fucosylation processes in esophageal epithelial cells.
2012

L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes.
2012

Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling.
2012

New fluorescent bile acids: Synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid
2012

Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease.
2012

Regulating the Regulator: Phosphorylation of PKC θ in T Cells.
2012

The two hit hypothesis: an improved method for siRNA-mediated gene silencing in stimulated primary human T cells.
2011

Advances in bile acid medicinal chemistry.
2011

Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.
2011

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion.
2011

Hepatitis C virus--T-cell responses and viral escape mutations.
2011

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection.
2011

New fluorescent bile acids: synthesis, chemical characterization, and disastereoselective uptake by Caco-2 cells of 3-deoxy 3-NBD-amino deoxycholic and ursodeoxycholic acid.
2011

Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites
2011

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.
2010

An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, downregulated in Barrett's oesophagus, which regulates NF-kappaB activation and cytokine levels.
2010

Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells.
2010

Bile acid toxicity structure activity relationships: Correlations between cell viability and lipophilicity in a panel of new and known bile acids using an esophageal cell line (HET-1A)
2010

Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
2010

Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells.
2010

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion.
2010

STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL
2010

Suppressor of cytokine signalling (SOCS) 1 and 3 enhance cell adhesion and inhibit migration towards the chemokine eotaxin/CCL11
2010

Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators.
2009

Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells
2009

STAT3 knockdown by siRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL.
2009

STAT3-stathmin interactions control microtubule dynamics in migrating T-cells.
2009

Shear stress induces internalization of E-cadherin and invasiveness in metastatic oesophageal cancer cells by a Src-dependent pathway.
2008

Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells.
2005

Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells.
2005

Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes.
2005

The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells.
2004

A multidisciplinary approach to the study of T cell migration.
2001

Cutting edge: protein kinase C beta expression is critical for export of Il-2 from T cells.
2000

Cross-linking of LFA-1 induces secretion of macrophage inflammatory protein (MIP)-lalpha and MIP-1beta with consequent directed migration of activated lymphocytes.
2000

High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy.
1997

Protein kinase C isotypes theta, delta and eta in human lymphocytes: differential responses to signalling through the T-cell receptor and phorbol esters
1997

Subcellular localization and translocation of protein kinase C isoforms zeta and epsilon in human peripheral blood lymphocytes
1996

Expression of CD44 and its variants on gastric epithelial cells of patients with Helicobacter pylori colonisation
1995

Autocrine regulation of the transcription factor NF kappa B by TNF alpha in the human T cell lymphoma line Hut 78.
1995

Expression of CD44 on rheumatoid synovial fluid lymphocytes
1995

Regulation of non-classical protein kinase C isoenzymes in a human T cell line.
1993

Conventional protein kinase C isoforms are not essential for cellular proliferation of a T cell lymphoma line.
1993

Neurofilament expression in human T lymphocytes
1993

Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell line
1992

Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line.

These arethe9 unique sources for Aideen Long's 71 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin Institute of Technology 3
Ireland -> Dublin Institute of Technology -> PubMed 2
Ireland -> Marine Institute 2
Ireland -> Royal College of Surgeons in Ireland 6
Ireland -> Royal College of Surgeons in Ireland -> PubMed 6
Ireland -> TU Dublin 2
Ireland -> Trinity College Dublin 61
Ireland -> Trinity College Dublin -> PubMed 31
Ireland -> University of Limerick 2

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