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Caoimhín G Concannon

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Details
Publications 46
As first author 4
As last author 2
Unique topics 353
Collaborations 65
Patents 1
Sources 3
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2016
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2012
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2016
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2016

Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
2016

Endoplasmic reticulum stress-mediated upregulation of miR-29a enhances sensitivity to neuronal apoptosis.
2016

Erratum to: Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
2016

Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer.
2015

Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
2015

ER Stress-Mediated Upregulation of miR-29a Enhances Sensitivity to Neuronal Apoptosis.
2015

MicroRNA-224 is Readily Detectable in Urine of Individuals with Diabetes Mellitus and is a Potential Indicator of Beta-Cell Demise.
2015

Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer.
2015

microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus.
2014

Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
2014

Increased expression of microRNA-29a in ALS mice: functional analysis of its inhibition.
2013

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
2013

CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures.
2013

Single-cell imaging of the heat-shock response in colon cancer cells suggests that magnitude and length rather than time of onset determines resistance to apoptosis.
2013

Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy.
2012

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
2012

Analyzing proteasomal subunit expression reveals Rpt4 as a prognostic marker in stage II colorectal cancer.
2012

Motoneurons secrete angiogenin to induce RNA cleavage in astroglia.
2012

Two step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate
2012

Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate.
2011

'Mild mitochondrial uncoupling' induced protection against neuronal excitotoxicity requires AMPK activity.
2011

Analyzing proteasomal subunit expression reveals Rpt4 as a prognostic marker in stage II colorectal cancer.
2011

Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation.
2011

Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy.
2010

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis.
2010

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis.
2010

AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF.
2010

Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation.
2010

Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation.
2010

Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo.
2010

Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition.
2010

Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability.
2010

INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighbouring Cells
2010

INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells.
2010

Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons.
2010

The amyloid precursor protein intracellular domain(AICD) disrupts actin dynamics and mitochondrial bioenergetics.
2009

Bid and calpains cooperate to trigger oxaliplatin-induced apoptosis of cervical carcinoma HeLa cells.
2009

Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma.
2009

Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation.
2008

Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects.
2008

Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects.
2008

Effects of transient focal cerebral ischemia in mice deficient in puma.
2007

NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner.
2006

Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.
2006

Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis.
2005

Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis.

These arethe3 unique sources for Caoimhín G Concannon's 46 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Royal College of Surgeons in Ireland 46
Ireland -> Royal College of Surgeons in Ireland -> PubMed 35
Ireland -> University College Dublin 1
Oct 3, 2012

TREATMENT AND PROGNOSIS OF SOLID TUMOUR CANCERS
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