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Catherine M Greene

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Microbiology

Details
Publications 150
As first author 28
As last author 35
Unique topics 793
Collaborations 88
Patents 1
Sources 9
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2017
2016
2015
2014
2013
2012
2011
2010
2009
Earlier
All
2017
2016
2015
2014
2013
2012
2011
2010
2009
Earlier

2017

Alpha-1 antitrypsin augmentation therapy decreases miR-199a-5p, miR-598 and miR-320a expression in monocytes via inhibition of NFκB.
2017

Best of Milan 2017-ERS Lung Science Conference session "Lung tissue repair and remodeling in chronic lung diseases: mechanisms and therapeutic approaches".
2017

Biopolymer-Based Nanoparticles for Cystic Fibrosis Lung Gene Therapy Studies.
2017

Challenges and future direction of molecular research in air pollution-related lung cancers.
2017

Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95).
2017

Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.
2017

Immune function? A missing link in the gender disparity in preterm neonatal outcomes.
2017

Innate Immunity of the Lung: From Basic Mechanisms to Translational Medicine.
2017

X Chromosome Encoded MicroRNAs are Functionally Increased in Cystic Fibrosis Monocytes.
2017

miR-CATCH Identifies Biologically Active miRNA Regulators of the Pro-Survival Gene XIAP, in Chinese Hamster Ovary Cells.
2016

Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis.
2016

Expression of X-linked Toll-like receptor 4 signaling genes in female vs. male neonates.
2016

High-throughput profiling for discovery of non-coding RNA biomarkers of lung disease.
2016

Identification of MiR-21-5p as a Functional Regulator of Mesothelin Expression Using MicroRNA Capture Affinity Coupled with Next Generation Sequencing.
2016

Reduced miR-659-3p Levels Correlate with Progranulin Increase in Hypoxic Conditions: Implications for Frontotemporal Dementia.
2016

Reduced pro-inflammatory responses to Staphylococcus aureus bloodstream infection and low prevalence of enterotoxin genes in isolates from patients on haemodialysis.
2016

Sexual maturation protects against development of lung inflammation through estrogen.
2016

The basophil surface marker CD203c identifies Aspergillus species sensitization in patients with cystic fibrosis.
2016

microRNA regulatory circuits in a mouse model of inherited retinal degeneration.
2016

α1-Antitrypsin deficiency.
2015

Developmental control of CFTR: from bioinformatics to novel therapeutic approaches.
2015

High-throughput profiling for discovery of non-coding RNA biomarkers of lung disease.
2015

MicroRNA Dysregulation in Cystic Fibrosis.
2015

Non-coding RNA as lung disease biomarkers.
2015

Sexual maturation protects against development of lung inflammation through estrogen.
2015

Short-chain Fatty Acids Cause an IL-8 Response in Cystic Fibrosis Airways via Increased GPR41.
2015

The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity.
2015

The Role of Short-Chain Fatty Acids, Produced by Anaerobic Bacteria, in the Cystic Fibrosis Airway.
2015

The basophil surface marker CD203c identifies Aspergillus species sensitization in patients with cystic fibrosis.
2015

Toll-Like Receptors in Cystic Fibrosis: Impact of Dysfunctional microRNA on Innate Immune Responses in the Cystic Fibrosis Lung.
2015

Transcription of Interleukin-8: How Altered Regulation Can Affect Cystic Fibrosis Lung Disease.
2015

Ursodeoxycholic acid inhibits TNFα-induced IL-8 release from monocytes.
2015

miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production.
2015

miR-CATCH: microRNA capture affinity technology.
2015

miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6.
2014

Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl- channels in Calu-3 airway epithelial cells.
2014

Chemical structure and biological activity of a highly branched (1 → 3,1 → 6)-β-D-glucan from Isochrysis galbana.
2014

Clarification of the risk of chronic obstructive pulmonary disease in α1-antitrypsin deficiency PiMZ heterozygotes.
2014

Cytokine responses to Staphylococcus aureus bloodstream infection differ between patient cohorts that have different clinical courses of infection.
2014

Long noncoding RNA are aberrantly expressed in vivo in the cystic fibrosis bronchial epithelium.
2014

Long noncoding RNAs in liver cancer: what we know in 2014.
2014

MicroRNA Dysregulation in Cystic Fibrosis.
2014

Non-coding RNA as lung disease biomarkers.
2014

Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis.
2014

Protein quality control in lung disease: it's all about cloud networking.
2014

Therapeutic aerosol bioengineering of siRNA for the treatment of inflammatory lung disease by TNFα gene silencing in macrophages.
2014

miR-199a-5p silencing regulates the unfolded protein response in chronic obstructive pulmonary disease and α1-antitrypsin deficiency.
2014

miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.
2014

miR-CATCH: microRNA capture affinity technology.
2014

miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6.
2013

Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique.
2013

Long noncoding RNA are aberrantly expressed in vivo in the cystic fibrosis bronchial epithelium.
2013

MicroRNA Expression in Cystic Fibrosis Airway Epithelium.
2013

MicroRNAs and liver cancer associated with iron overload: therapeutic targets unravelled.
2013

Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis.
2013

Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in ΔF508 cystic fibrosis airway epithelium.
2013

Targeting miRNA-based medicines to cystic fibrosis airway epithelial cells using nanotechnology.
2013

microRNAs in asthma: potential therapeutic targets.
2012

Effect of Estrogen on Pseudomonas Mucoidy and Exacerbations in Cystic Fibrosis
2012

Effect of estrogen on pseudomonas mucoidy and exacerbations in cystic fibrosis.
2012

Is there a therapeutic role for selenium in alpha-1 antitrypsin deficiency?
2012

The effect of Aspergillus fumigatus infection on vitamin D receptor expression in cystic fibrosis.
2012

Therapeutic modulation of miRNA for the treatment of proinflammatory lung diseases.
2012

Ventriculoperitoneal shunt-related infections caused by Staphylococcus epidermidis: pathogenesis and implications for treatment.
2012

microRNAs in asthma: potential therapeutic targets.
2011

High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations.
2011

In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens.
2011

Measurement of the unfolded protein response (UPR) in monocytes.
2011

Measurement of the unfolded protein response (UPR) in monocytes.
2011

Mechanisms of protein misfolding in conformational lung diseases.
2011

Pulmonary Inflammation in Cystic Fibrosis: Impact of Innate Immunity and Estrogen
2011

Quantification and evaluation of the role of antielastin autoantibodies in the emphysematous lung.
2011

The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and α-1 anti-trypsin deficiency.
2010

17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor.
2010

Alpha-1 antitrypsin deficiency.
2010

Candida species in cystic fibrosis: A road less travelled.
2010

Editorial: How Can We Target Pulmonary Inflammation in Cystic Fibrosis?
2010

Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency.
2010

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.
2010

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.
2010

Gain of function effects of Z alpha-1 antirypsin
2010

High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations.
2010

Inhibition of Toll-Like Receptor 2-Mediated Interleukin-8 Production in Cystic Fibrosis Airway Epithelial Cells via the α7-Nicotinic Acetylcholine Receptor
2010

MicroRNAs in inflammatory lung disease--master regulators or target practice?
2010

Protein misfolding and obstructive lung disease.
2010

Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway.
2010

Quantification and evaluation of the role of antielastin autoantibodies in the emphysematous lung.
2010

TLR3 Sensing of Viral Infection
2010

Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response
2010

Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response.
2010

miR-126 Is Downregulated in Cystic Fibrosis Airway Epithelial Cells and Regulates TOM1 Expression.
2010

miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression.
2009

Alpha-1 antitrypsin deficiency.
2009

Anti-proline-glycine-proline or antielastin autoantibodies are not evident in chronic inflammatory lung disease.
2009

Biofilm characteristics of Staphylococcus epidermidis isolates associated with device-related meningitis.
2009

Community-acquired pneumonia in older patients: does age influence systemic cytokine levels in community-acquired pneumonia?
2009

Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency
2009

Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency.
2009

LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic saline.
2009

Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery.
2009

Proteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery.
2009

Selenoprotein S/SEPS1 modifies endoplasmic reticulum stress in Z variant alpha1-antitrypsin deficiency.
2009

Staphylococcus epidermidis polysaccharide intercellular adhesin induces IL-8 expression in human astrocytes via a mechanism involving TLR2.
2008

Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.
2008

Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.
2008

Alpha-1 antitrypsin deficiency: a conformational disease associated with lung and liver manifestations.
2008

Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro.
2008

Biofilm and the role of the ica operon and aap in Staphylococcus epidermidis isolates causing neurosurgical meningitis.
2008

Biofilm and the role of the ica operon and aap in Staphylococcus epidermidis isolates causing neurosurgical meningitis.
2008

Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis.
2008

Staphylococcus epidermidis polysaccharide intercellular adhesin induces IL-8 expression in human astrocytes via a mechanism involving TLR2.
2008

Targeting neutrophil elastase in cystic fibrosis.
2008

Toll-like receptors as therapeutic targets in cystic fibrosis.
2008

Toll-like receptors as therapeutic targets in cystic fibrosis.
2007

Alpha-1 antitrypsin deficiency: a conformational disease associated with lung and liver manifestations.
2007

Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke.
2007

Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke.
2007

Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression.
2007

Neutrophil elastase up-regulates cathepsin B and matrix metalloprotease-2 expression.
2007

Secretory leucocyte protease inhibitor inhibits interferon-gamma-induced cathepsin S expression.
2007

Secretory leucocyte protease inhibitor inhibits interferon-gamma-induced cathepsin S expression.
2007

Tauroursodeoxycholic acid inhibits apoptosis induced by Z alpha-1 antitrypsin via inhibition of Bad.
2006

Antimicrobial proteins and polypeptides in pulmonary innate defence.
2006

Effect of pro-inflammatory stimuli on mucin expression and inhibition by secretory leucoprotease inhibitor.
2006

Elafin prevents lipopolysaccharide-induced AP-1 and NF-kappaB activation via an effect on the ubiquitin-proteasome pathway.
2006

Elafin prevents lipopolysaccharide-induced AP-1 and NF-kappaB activation via an effect on the ubiquitin-proteasome pathway.
2005

Antimicrobial proteins and polypeptides in pulmonary innate defence.
2005

Elastolytic proteases: inflammation resolution and dysregulation in chronic infective lung disease.
2005

Endotoxin up-regulates interleukin-18: potential role for gram-negative colonization in sarcoidosis.
2005

Respiratory epithelial cells require Toll-like receptor 4 for induction of human beta-defensin 2 by lipopolysaccharide.
2005

Respiratory epithelial cells require Toll-like receptor 4 for induction of human beta-defensin 2 by lipopolysaccharide.
2005

Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding.
2005

TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells.
2005

Toll-like receptor expression and function in airway epithelial cells.
2005

Viral inhibition of IL-1- and neutrophil elastase-induced inflammatory responses in bronchial epithelial cells.
2004

Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency.
2004

Loss of microbicidal activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis.
2004

Secretory leucoprotease inhibitor impairs Toll-like receptor 2- and 4-mediated responses in monocytic cells.
2004

Z alpha1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant.
2003

Association of IL-10 polymorphism with severity of illness in community acquired pneumonia.
2003

Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins.
2003

Neutrophil elastase up-regulates human beta-defensin-2 expression in human bronchial epithelial cells.
2002

Ambient pCO2 modulates intracellular pH, intracellular oxidant generation, and interleukin-8 secretion in human neutrophils.
2002

Local impairment of anti-neutrophil elastase capacity in community-acquired pneumonia.
2002

Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination.
2002

Tumor necrosis factor-alpha-converting enzyme: its role in community-acquired pneumonia.
2001

Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor.
2001

Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium.
2000

Role of IL-18 in CD4+ T lymphocyte activation in sarcoidosis.
1998

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants.

These arethe9 unique sources for Catherine M Greene's 150 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 2
Ireland -> Dublin City University -> PubMed 2
Ireland -> Maynooth University 1
Ireland -> Royal College of Surgeons in Ireland 145
Ireland -> Royal College of Surgeons in Ireland -> PubMed 98
Ireland -> TU Dublin (Tallaght Campus) 2
Ireland -> TU Dublin (Tallaght Campus) -> PubMed 2
Ireland -> Trinity College Dublin 2
Ireland -> University College Dublin 1
Apr 16, 2013

Selective isolation of a messenger RNA molecule having its cognate micro RNA molecules bound thereto
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