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Caroline A Jefferies

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Microbiology

Details
Publications 50
As first author 4
As last author 31
Unique topics 403
Collaborations 41
Sources 8
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All
2017
2016
2014
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2012
2011
2010
2009
2008
Earlier
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2017
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2014
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2012
2011
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2008
Earlier

2017

MicroRNA-302d targets IRF9 to regulate the IFN-induced gene expression in SLE.
2017

The RNA binding protein La/SS-B promotes RIG-I-mediated type I and type III IFN responses following Sendai viral infection.
2016

Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon.
2014

Btk Regulates Macrophage Polarization in Response to Lipopolysaccharide
2014

High-throughput methods for screening liposome-macrophage cell interaction.
2014

Isolation of microRNA from conjunctival impression cytology.
2014

Role of DNA/RNA sensors and contribution to autoimmunity.
2014

TRIM68 Negatively Regulates IFN-b Production by Degrading TRK Fused Gene, a Novel Driver of IFN-b Downstream of Anti-Viral Detection Systems
2014

TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems.
2014

TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.
2014

The association of cytokines with disease activity and damage scores in systemic lupus erythematosus patients.
2013

Bruton's tyrosine kinase is required for apoptotic cell uptake via regulating the phosphorylation and localization of calreticulin.
2013

Btk regulates macrophage polarization in response to lipopolysaccharide.
2013

Elevated B lymphocyte stimulator levels are associated with increased damage in an Irish systemic lupus erythematosus cohort.
2013

Estrogen receptor α regulates tripartite motif-containing protein 21 expression, contributing to dysregulated cytokine production in systemic lupus erythematosus.
2013

IRF5-mediated signaling and implications for SLE.
2013

TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems.
2012

Defects in Acute Rsponses to TLR4 in Btk-deficient Mice Result in Impaired Dendritic Cell-induced IFN-γ Production by Natural Killer Cells
2012

Defects in acute responses to TLR4 in Btk-deficient mice result in impaired dendritic cell-induced IFN-γ production by natural killer cells
2012

Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus.
2012

Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-κB signaling in neurons.
2012

Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-κB signaling in neurons.
2012

Genetics of SLE: Functional Relevance for Monocytes/Macrophages in Disease
2012

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase a oncogene.
2012

Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.
2011

Antiviral TRIMs: Friend or Foe in Autoimmune and Autoinflammatory Disease?
2011

Defects in acute responses to TLR4 in Btk-deficient mice result in impaired dendritic cell-induced IFN-γ production by natural killer cells.
2011

Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus.
2011

Evaluation and optimization of IgY spin column technology in the depletion of abundant proteins from human serum.
2011

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.
2011

TLR-induced activation of Btk -- role for endosomal MHC class II molecules revealed.
2011

Targeted liposomal drug delivery to monocytes and macrophages.
2011

Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.
2010

Evaluation and optimization of IgY spin column technology in the depletion of abundant proteins from human serum.
2010

Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors
2010

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors.
2010

Targeted liposomal drug delivery to monocytes and macrophages.
2009

2D-DIGE: comparative proteomics of cellular signalling pathways.
2009

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
2009

Proteomic analysis of protein complexes in Toll-like receptor biology.
2008

Targeting IRFs by ubiquitination: regulating antiviral responses.
2008

Targeting IRFs by ubiquitination: regulating antiviral responses.
2008

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3.
2007

NF-kB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1
2007

Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.
2006

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction
2005

Interferon gene regulation: not all roads lead to Tolls.
2003

Interferon Regulatory Factor-3-mediated Activation of the Interferon-sensitive Response Element by Toll-like receptor (TLR) 4 but Not TLR3 Requires the p65 Subunit of NF-κB
2003

Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors.
2001

Involvement of the low molecular weight G protein Rac1 in IL-1 signalling to NFkB activation

These arethe8 unique sources for Caroline A Jefferies's 50 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin Institute of Technology 8
Ireland -> Dublin Institute of Technology -> PubMed 2
Ireland -> Maynooth University 2
Ireland -> Royal College of Surgeons in Ireland 34
Ireland -> Royal College of Surgeons in Ireland -> PubMed 24
Ireland -> TU Dublin 6
Ireland -> Trinity College Dublin 6
Ireland -> Trinity College Dublin -> PubMed 2

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