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Elaine W Kay

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Medicine & Nursing

Details
Publications 157
As first author 5
As last author 19
Unique topics 944
Collaborations 192
Sources 13
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2019
2018
2017
2016
2015
2014
2013
2012
2011
Earlier
All
2019
2018
2017
2016
2015
2014
2013
2012
2011
Earlier

2019

Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis
2018

Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH).
2018

Measurement of the IgM and IgG Autoantibody Immune Responses in Human Serum has High Predictive Value for the Presence of Colorectal Cancer.
2017

A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer.
2017

BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer.
2017

Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings.
2017

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.
2017

Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.
2017

Investigating the role of the IGF axis as a predictor of biochemical recurrence in prostate cancer patients post-surgery.
2017

Stromal TRIM28-associated signaling pathway modulation within the colorectal cancer microenvironment.
2017

The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.
2017

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation.
2016

A stepwise integrated approach to personalized risk predictions in stage III colorectal cancer.
2016

Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach.
2016

BCL-2 system analysis identifies high-risk colorectal cancer patients.
2016

Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
2016

Erratum to: Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
2016

Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential.
2016

HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients.
2016

Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach.
2016

Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology.
2016

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.
2016

Tamoxifen Suppresses the Growth of Malignant Pleural Mesothelioma Cells.
2016

Tamoxifen Suppresses the Growth of Malignant Pleural Mesothelioma Cells.
2016

Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer.
2016

The impact of ERBB-family germline single nucleotide polymorphisms on survival response to adjuvant trastuzumab treatment in HER2-positive breast cancer.
2016

The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation.
2015

Altered expression of caspases-4 and -5 during inflammatory bowel disease and colorectal cancer: Diagnostic and therapeutic potential.
2015

CD44 increases the efficiency of distant metastasis of breast cancer.
2015

Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
2015

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.
2015

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.
2015

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.
2015

Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer.
2015

LC3B globular structures correlate with survival in esophageal adenocarcinoma
2015

LC3B globular structures correlate with survival in esophageal adenocarcinoma.
2015

Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach.
2015

Relationship between serum response factor and androgen receptor in prostate cancer.
2015

Targeting the 19S proteasomal subunit, Rpt4, for the treatment of colon cancer.
2015

Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer.
2014

BCL2 protein signalling determines acute responses to neoadjuvant chemoradiotherapy in rectal cancer.
2014

CD44 increases the efficiency of distant metastasis of breast cancer.
2014

Diagnostic potential of zinc finger protein-specific autoantibodies and associated linear B-cell epitopes in colorectal cancer.
2014

Differential p16/INK4A cyclin-dependent kinase inhibitor expression correlates with chemotherapy efficacy in a cohort of 88 malignant pleural mesothelioma patients.
2014

Global DNA methylation is altered by neoadjuvant chemoradiotherapy in rectal cancer and may predict response to treatment - A pilot study.
2014

High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer.
2014

Protective role for caspase-11 during acute experimental murine colitis.
2013

High coexpression of both EGFR and IGF1R correlates with poor patient prognosis in resected non-small-cell lung cancer.
2013

Relationship between epithelial and stromal TRIM28 expression predicts survival in colorectal cancer patients.
2013

Spindle assembly checkpoint protein expression correlates with cellular proliferation and shorter time to recurrence in ovarian cancer.
2013

Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy.
2013

The analysis of serum response factor expression in bone and soft tissue prostate cancer metastases.
2012

Activated eosinophils in association with enteric nerves in inflammatory bowel disease.
2012

Analyzing proteasomal subunit expression reveals Rpt4 as a prognostic marker in stage II colorectal cancer.
2012

CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.
2012

Identification of transcription factors associated with castration-resistance: Is the serum responsive factor a potential therapeutic target?
2012

Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling.
2012

Junctional adhesion molecule-A is co-expressed with HER2 in breast tumors and acts as a novel regulator of HER2 protein degradation and signaling.
2011

Analysis of APC allelic imbalance/loss of heterozygosity and APC protein expression in cutaneous squamous cell carcinomas.
2011

Analyzing proteasomal subunit expression reveals Rpt4 as a prognostic marker in stage II colorectal cancer.
2011

Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy.
2011

Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer.
2011

Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer.
2011

Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer.
2011

MMP9 expression in oesophageal adenocarcinoma is upregulated with visceral obesity and is associated with poor tumour differentiation.
2011

Phage display biopanning identifies the translation initiation and elongation factors (IF1α-3 and eIF-3) as components of Hsp70-peptide complexes in breast tumour cells.
2011

Pravastatin reduces Marfan aortic dilation.
2011

RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer.
2011

Sustained Expression of Steroid Receptor Coactivator SRC-2/TIF-2 is Associated with Better Prognosis in Malignant Pleural Mesothelioma.
2011

Sustained expression of steroid receptor coactivator SRC-2/TIF-2 is associated with better prognosis in malignant pleural mesothelioma.
2011

The role of secreted frizzled-related protein 2 expression in prostate cancer.
2010

Ensemble based system for whole-slide prostate cancer probability mapping using color texture features.
2010

Evaluation of Zinc-alpha-2-Glycoprotein and Proteasome Subunit beta-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology.
2010

Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer
2010

Integrating biobanks: addressing the practical and ethical issues to deliver a valuable tool for cancer research.
2010

MAD2 downregulation in hypoxia is independent of promoter hypermethylation.
2009

Carbonic anhydrase IX expression in prostate cancer.
2009

Cell encapsulation within PVA-based hydrogels via freeze-thawing: a one-step scaffold formation and cell storage technique.
2009

Has the ThinPrep method of cervical screening maintained its improvement over conventional smears in terms of specimen adequacy?
2009

Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer.
2009

Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.
2009

Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.
2009

Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer.
2008

Analysis of FHIT allelic imbalance/loss of heterozygosity and FHIT expression in cutaneous squamous cell carcinomas.
2008

GIST with a twist--upregulation of PDGF-B resulting in metachronous gastrointestinal stromal tumor and dermatofibrosarcoma protuberans.
2008

Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer.
2008

Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer.
2008

Recurrence of urothelial carcinoma of the bladder: a role for insulin-like growth factor-II loss of imprinting and cytoplasmic E-cadherin immunolocalization.
2008

The difficulty with audit of high grade cervical cytology in the absence of a national screening programme.
2008

Urinary insulin-like growth factor 2 identifies the presence of urothelial carcinoma of the bladder.
2007

Alpha-T-catenin (CTNNA3) displays tumour specific monoallelic expression in urothelial carcinoma of the bladder.
2007

Formalin-fixed paraffin-embedded clinical tissues show spurious copy number changes in array-CGH profiles.
2007

Formalin-fixed paraffin-embedded clinical tissues show spurious copy number changes in array-CGH profiles.
2007

Immunoreactivity of p53, Mdm2, p21(WAF1/CIP1) Bcl-2, and Bax in soft tissue sarcomas: correlation with histologic grade.
2007

Molecular genetic analysis of the BRCA2 tumor suppressor gene region in cutaneous squamous cell carcinomas.
2006

Analysis of p16 expression and allelic imbalance / loss of heterozygosity of 9p21 in cutaneous squamous cell carcinomas.
2006

Disruption of COX-2 modulates gene expression and the cardiac injury response to doxorubicin.
2006

Enhanced detection of microsatellite instability and mismatch repair gene expression in cutaneous squamous cell carcinomas.
2006

Iloprost attenuates doxorubicin-induced cardiac injury in a murine model without compromising tumour suppression.
2006

The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microarrays on line.
2006

The higher incidence of squamous cell carcinoma in renal transplant recipients is associated with increased telomere lengths.
2006

Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival.
2005

A simple antigen retrieval method for the optimal demonstration of cyclin-D1 overexpression in formalin-fixed paraffin-embedded cases of mantle cell lymphoma.
2005

Association between cyclooxygenase-2-expressing macrophages, ulceration and microvessel density in colorectal cancer.
2005

Loss of p16INK4A expression is associated with allelic imbalance/loss of heterozygosity of chromosome 9p21 in microdissected synovial sarcomas.
2005

The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microarrays on line.
2004

Cytokeratin 7/20 and MUC1, 2, 5AC, and 6 expression patterns in Barrett's esophagus and intestinal metaplasia of the stomach: intestinal metaplasia of the cardia is related to Barrett's esophagus.
2004

The relationship between cyclooxygenase-2 expression and characteristics of malignant transformation in human colorectal adenomas.
2004

Use of tissue microarray for interlaboratory validation of HER2 immunocytochemical and FISH testing.
2003

Borderline nuclear change in cervical smears: five-year follow-up.
2003

Differences in proximal (cardia) versus distal (antral) gastric carcinogenesis via the retinoblastoma pathway.
2003

Effect of neoadjuvant chemoradiotherapy on angiogenesis in oesophageal cancer.
2003

Long-term protective effects of hypothermia on reperfusion injury post-testicular torsion.
2003

Neoadjuvant antiangiogenic therapy with tamoxifen does not impair gastrointestinal anastomotic repair in the rat.
2003

Pharmacological induction of HSP27 attenuates intimal hyperplasia in vivo.
2003

Prognostic relevance of Fas (APO-1/CD95) ligand in human colorectal cancer.
2003

The problem with KIT: clinical implications and practical difficulties with CD117 immunostaining.
2002

Comparative study: conventional cervical and ThinPrep Pap tests in a routine clinical setting.
2002

Comparison of the expression of p53, p21, Bax and the induction of apoptosis between patients with basal cell carcinoma and normal controls in response to ultraviolet irradiation.
2002

Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer.
2002

Exogenous and endogenous angiogenic stimuli do not augment splenic autotransplantation.
2002

Infiltrating immune cells, but not tumour cells, express FasL in non-small cell lung cancer: No association with prognosis identified in 3-year follow-up.
2002

Loss of Fhit expression as a potential marker of malignant progression in preinvasive squamous cervical cancer.
2002

Telomerase activity detected in oral lichen planus by RNA in situ hybridisation: not a marker for malignant transformation.
2001

A high degree of chromosomal instability at 13q14 in cutaneous squamous cell carcinomas: indication for a role of a tumour suppressor gene other than Rb.
2001

Altered p53 expression in benign and malignant skin lesions from renal transplant recipients and immunocompetent patients with skin cancer: correlation with human papillomaviruses?
2001

CD44V6 in gastric carcinoma: a marker of tumor progression.
2001

Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer.
2001

Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma: tumor size and lymph node status remain the most important prognostic features.
2001

P53 CODON 72 POLYMORPHISM AND HUMAN PAPILLOMAVIRUS ASSOCIATED SKIN CANCER
2001

Poor agreement in recognition of abnormal mitoses: requirement for standardized and robust definitions.
2001

Role of taurine in preventing acetaminophen-induced hepatic injury in the rat.
2001

TGF-beta1 is elevated in breast cancer tissue and regulates nitric oxide production from a number of cellular sources during hypoxia re-oxygenation injury.
2001

The role of apoptotic cell death in cardiovascular disease.
2000

A simple and rapid technique for the detection of Epstein-Barr virus DNA in HIV-associated oral hairy leukoplakia biopsies.
2000

Diaphragmatic dysfunction secondary to experimental lower torso ischaemia-reperfusion injury is attenuated by thermal preconditioning.
2000

Immunohistochemical expression of nm23 in primary invasive malignant melanoma is predictive of survival outcome.
2000

Replication error phenotype, clinicopathological variables, and patient outcome in Dukes' B stage II (T3,N0,M0) colorectal cancer.
2000

Taurine protects against early and late skeletal muscle dysfunction secondary to ischaemia reperfusion injury.
1999

Phenotyping of immune cell infiltrates in breast and colorectal tumours.
1999

The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease
1998

Identification of vertical growth phase in malignant melanoma. A study of interobserver agreement.
1998

Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1.
1997

Determination of testicular function after torsion by DNA flow cytometry of serial fine-needle aspirates.
1997

Loss of heterozygosity and microsatellite instability at the DCC and nm23 loci in Duke's B colorectal carcinoma.
1997

Mild abnormalities in liver histology associated with chronic hepatitis: distinction from normal liver histology.
1997

Ploidy profile of morphologically normal squamous epithelium adjacent to high grade cervical intraepithelial neoplasia.
1996

An image analysis study of DNA content in early colorectal cancer.
1996

Inter-observer variation of p53 immunohistochemistry--an assessment of a practical problem and comparison with other studies.
1996

Proliferation indexes--a comparison between cutaneous basal and squamous cell carcinomas.
1995

DNA quantification is technically feasible and of value in cervical smear samples: possible applications for determination of progression in low grade dyskaryosis.
1995

The pathology of cervical cancer.
1995

ras and p53 in the prediction of survival in Dukes' stage B colorectal carcinoma.
1994

Cytoplasmic c-erbB-2 protein expression correlates with survival in Dukes' B colorectal carcinoma.
1994

Oxygen free radical activity in experimental colonic carcinoma.
1993

Lymphoepithelioma-like carcinoma of the uterine cervix with c-erbB-2, p53 oncoprotein expression and DNA quantification.
1993

Stress ulceration and gastric mucosal cell kinetics: the influence of prophylaxis against acute stress ulceration.

These arethe13 unique sources for Elaine W Kay's 157 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 12
Ireland -> Dublin City University -> PubMed 12
Ireland -> National University of Ireland Galway 1
Ireland -> National University of Ireland Galway -> PubMed 1
Ireland -> Royal College of Surgeons in Ireland 112
Ireland -> Royal College of Surgeons in Ireland -> PubMed 90
Ireland -> TU Dublin (Blanchardstown Campus) 1
Ireland -> TU Dublin (Blanchardstown Campus) -> PubMed 1
Ireland -> Trinity College Dublin 11
Ireland -> Trinity College Dublin -> PubMed 7
Ireland -> University College Cork 1
Ireland -> University College Dublin 21
Ireland -> University College Dublin -> PubMed 21

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