Dublin City University
|As first author||8|
|As last author||5|
Elaine W Kay(7)
K M Sheehan(3)
David J Kinahan(2)
Jochen H M Prehn(2)
F E Murray(2)
... and 5 others
These arethe4 unique sources for Gregor Kijanka's 20 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.
|Ireland -> Dublin City University||13|
|Ireland -> Dublin City University -> PubMed||12|
|Ireland -> Royal College of Surgeons in Ireland||7|
|Ireland -> Royal College of Surgeons in Ireland -> PubMed||4|
A method of predicting the likelihood of a patient with a solid tumor cancer or a metastasis thereof responding to cancer therapy comprises the steps of assaying a sample of the primary solid tumor or a local or distant metastasis thereof obtained from the patient to determine a level of expression of CerS5, and if an elevated CerS5 expression level is detected in the sample from the patient, then predicting a likelihood that the patient will have a positive clinical response to cancer therapy, or if a non-elevated CerS5 expression level is detected in the sample from the patient, then predicting a likelihood that the patient will have a negative clinical response to cancer therapy.
The invention relates to a method of screening a patient to identify and quantify risk of colorectal cancer, and thereby identify patients suitable for further invasive investigation such as a colonoscopy. The method employs auto-antibodies that are shown to correlate with colorectal cancer risk method and involves of assaying a biological sample from the individual for a combination of a plurality of biomarkers selected from SEQUENCE ID NO's: 1 to 12, where the combination of biomarkers is chosen such that detection of all biomarkers in the patient correlates to at least a 50% risk of the patient being positive for colorectal cancer. Detection of all of the combination of biomarkers indicates that the patient should undergo a colonoscopy. Kits for performing the method of the invention are also provided.
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