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Heiko Düssmann

Institution

Royal College of Surgeons in Ireland

Contact

Subjects

Biochemistry

Details
Publications 45
As first author 2
As last author 0
Unique topics 377
Collaborations 41
Patents 1
Sources 6
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2019
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2016
2015
2014
2013
2012
2011
2010
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2019
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2016
2015
2014
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2012
2011
2010
Earlier

2019

The anti-inflammatory compound candesartan cilexetil improves neurological outcomes in a mouse model of neonatal hypoxia
2017

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform.
2017

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.
2017

Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells.
2016

Single-cell time-lapse imaging of intracellular O2 in response to metabolic inhibition and mitochondrial cytochrome-c release.
2016

Time-lapse imaging of p65 and IκBα translocation kinetics following Ca(2+)-induced neuronal injury reveals biphasic translocation kinetics in surviving neurons.
2015

AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells.
2015

BH3-Only protein bmf is required for the maintenance of glucose homeostasis in an in vivo model of HNF1α-MODY diabetes
2015

BH3-Only protein bmf is required for the maintenance of glucose homeostasis in an in vivo model of HNF1α-MODY diabetes.
2015

Bax regulates neuronal Ca2+ homeostasis.
2015

Versatile Conjugated Polymer Nanoparticles for High-Resolution O2 Imaging in Cells and 3D Tissue Models.
2014

Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
2014

Single-Cell Imaging of Bioenergetic Responses to Neuronal Excitotoxicity and Oxygen and Glucose Deprivation
2014

Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation.
2013

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
2013

Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability.
2013

Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability.
2013

Single-cell imaging of the heat-shock response in colon cancer cells suggests that magnitude and length rather than time of onset determines resistance to apoptosis.
2012

A structured approach to the study of metabolic control principles in intact and impaired mitochondria.
2012

A structured approach to the study of metabolic control principles in intact and impaired mitochondria.
2012

AMP-activated protein kinase (AMPK)-induced preconditioning in primary cortical neurons involves activation of MCL-1.
2012

Calpains are downstream effectors of bax-dependent excitotoxic apoptosis.
2012

Calpains are downstream effectors of bax-dependent excitotoxic apoptosis.
2012

Motoneurons secrete angiogenin to induce RNA cleavage in astroglia.
2012

Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.
2012

Two step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate
2012

Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate.
2011

Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation.
2011

Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release.
2011

Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.
2010

Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release.
2010

INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighbouring Cells
2010

INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells.
2009

ALISSA: an automated live-cell imaging system for signal transduction analyses.
2009

Bid and calpains cooperate to trigger oxaliplatin-induced apoptosis of cervical carcinoma HeLa cells.
2009

Dynamics of outer mitochondrial membrane permeabilization during apoptosis.
2009

Dynamics of outer mitochondrial membrane permeabilization during apoptosis.
2009

Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation.
2008

Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein.
2008

Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation.
2007

Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance.
2007

The Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization.
2005

Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein.
2002

Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.
2001

Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis.

These arethe6 unique sources for Heiko Düssmann's 45 publications. A single publication may appear in multiple sources. Click on a name or publication count to see the publications for a particular source.

Source #
Ireland -> Dublin City University 1
Ireland -> Dublin City University -> PubMed 1
Ireland -> Maynooth University 1
Ireland -> Royal College of Surgeons in Ireland 43
Ireland -> Royal College of Surgeons in Ireland -> PubMed 30
Ireland -> University College Cork 1
Sep 29, 2010

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