Type

Journal Article

Authors

Jonathan Bones
Anna Lindeberg
Amy Farrell
Clair Gallagher
Christian Kaisermayer
Simone Albrecht

Subjects

Biochemistry

Topics
cell viability cell death proteomics protein dynamics media product quality cho cells apoptosis protein

Proteomics in biomanufacturing control: Protein dynamics of CHO-K1 cells and conditioned media during apoptosis and necrosis. (2017)

Abstract Cell viability has a critical impact on product quantity and quality during the biomanufacturing of therapeutic proteins. An advanced understanding of changes in the cellular and conditioned media proteomes upon cell stress and death is therefore needed for improved bioprocess control. Here, a high pH/low pH reversed phase data independent 2D-LC-MS
Collections Ireland -> Dublin City University -> PubMed

Full list of authors on original publication

Jonathan Bones, Anna Lindeberg, Amy Farrell, Clair Gallagher, Christian Kaisermayer, Simone Albrecht

Experts in our system

1
Jonathan Bones
University College Dublin
Total Publications: 28
 
2
Amy Farrell
Dublin City University
Total Publications: 4
 
3
Clair Gallagher
Dublin City University
Total Publications: 17