Type

Journal Article

Authors

Robert Whelan
Richard B Reilly
Niall Tubridy
Michael Hutchinson
Teresa Burke
Jessica Bramham
Katie Kinsella
Marie Claire O'Brien
Siobhan Kelly
Róisín Lonergan
and 4 others

Subjects

Psychology

Topics
learning methods information processing machine learning event related potentials speed cognitive processing multiple sclerosis patients

Machine Learning EEG to Predict Cognitive Functioning and Processing Speed Over a 2-Year Period in Multiple Sclerosis Patients and Controls. (2017)

Abstract Event-related potentials (ERPs) show promise to be objective indicators of cognitive functioning. The aim of the study was to examine if ERPs recorded during an oddball task would predict cognitive functioning and information processing speed in Multiple Sclerosis (MS) patients and controls at the individual level. Seventy-eight participants (35 MS patients, 43 healthy age-matched controls) completed visual and auditory 2- and 3-stimulus oddball tasks with 128-channel EEG, and a neuropsychological battery, at baseline (month 0) and at Months 13 and 26. ERPs from 0 to 700 ms and across the whole scalp were transformed into 1728 individual spatio-temporal datapoints per participant. A machine learning method that included penalized linear regression used the entire spatio-temporal ERP to predict composite scores of both cognitive functioning and processing speed at baseline (month 0), and months 13 and 26. The results showed ERPs during the visual oddball tasks could predict cognitive functioning and information processing speed at baseline and a year later in a sample of MS patients and healthy controls. In contrast, ERPs during auditory tasks were not predictive of cognitive performance. These objective neurophysiological indicators of cognitive functioning and processing speed, and machine learning methods that can interrogate high-dimensional data, show promise in outcome prediction.
Collections Ireland -> Dublin City University -> PubMed

Full list of authors on original publication

Robert Whelan, Richard B Reilly, Niall Tubridy, Michael Hutchinson, Teresa Burke, Jessica Bramham, Katie Kinsella, Marie Claire O'Brien, Siobhan Kelly, Róisín Lonergan and 4 others

Experts in our system

1
Robert Whelan
Trinity College Dublin
Total Publications: 65
 
2
Richard Reilly
Trinity College Dublin
Total Publications: 185
 
3
Niall Tubridy
University College Dublin
Total Publications: 23
 
4
Michael Hutchinson
University College Dublin
Total Publications: 79
 
5
Teresa Burke
Dublin City University
Total Publications: 20
 
6
Jessica Bramham
University College Dublin
Total Publications: 19
 
7
Katie Kinsella
Trinity College Dublin
Total Publications: 14
 
8
Marie Claire O'Brien
Dublin City University
Total Publications: 4
 
9
Siobhán Kelly
Trinity College Dublin
Total Publications: 9
 
10
R Lonergan
University College Dublin
Total Publications: 14