Journal Article


Richard B Reilly
Richard W Costello
Imran Sulaiman
Céline De Looze
Yaniv Zigel
Terence E Taylor


Medicine & Nursing

patient outcomes this review drug delivery drug delivery systems disease control clinical practice health care health professionals

Advances in Audio-Based Systems to Monitor Patient Adherence and Inhaler Drug Delivery. (2017)

Abstract Hundreds of millions of people worldwide have asthma and COPD. Current medications to control these chronic respiratory diseases can be administered using inhaler devices, such as the pressurized metered dose inhaler and the dry powder inhaler. Provided that they are used as prescribed, inhalers can improve patient clinical outcomes and quality of life. Poor patient inhaler adherence (both time of use and user technique) is, however, a major clinical concern and is associated with poor disease control, increased hospital admissions, and increased mortality rates, particularly in low- and middle-income countries. There are currently limited methods available to health-care professionals to objectively and remotely monitor patient inhaler adherence. This review describes recent sensor-based technologies that use audio-based approaches that show promising opportunities for monitoring inhaler adherence in clinical practice. This review discusses how one form of sensor-based technology, audio-based monitoring systems, can provide clinically pertinent information regarding patient inhaler use over the course of treatment. Audio-based monitoring can provide health-care professionals with quantitative measurements of the drug delivery of inhalers, signifying a clear clinical advantage over other methods of assessment. Furthermore, objective audio-based adherence measures can improve the predictability of patient outcomes to treatment compared with current standard methods of adherence assessment used in clinical practice. Objective feedback on patient inhaler adherence can be used to personalize treatment to the patient, which may enhance precision medicine in the treatment of chronic respiratory diseases.
Collections Ireland -> Royal College of Surgeons in Ireland -> PubMed

Full list of authors on original publication

Richard B Reilly, Richard W Costello, Imran Sulaiman, Céline De Looze, Yaniv Zigel, Terence E Taylor

Experts in our system

Richard Reilly
Trinity College Dublin
Total Publications: 195
Richard W Costello
Royal College of Surgeons in Ireland
Total Publications: 69
Imran Sulaiman
Royal College of Surgeons in Ireland
Total Publications: 26
Céline De Looze
Trinity College Dublin
Total Publications: 3
Terence Taylor
Royal College of Surgeons in Ireland
Total Publications: 11