Type

Journal Article

Authors

Tanya Parish
Stephen V Gordon

Subjects

Microbiology

Topics
drug resistance growth rate profile cell wall mycobacterium tuberculosis humans microbial culture

Microbe Profile: Mycobacterium tuberculosis: Humanity's deadly microbial foe. (2018)

Abstract Mycobacterium tuberculosis is an expert and deadly pathogen, causing the disease tuberculosis (TB) in humans. It has several notable features: the ability to enter non-replicating states for long periods and cause latent infection; metabolic remodelling during chronic infection; a thick, waxy cell wall; slow growth rate in culture; and intrinsic drug resistance and antibiotic tolerance. As a pathogen, M. tuberculosis has a complex relationship with its host, is able to replicate inside macrophages, and expresses diverse immunomodulatory molecules. M. tuberculosis currently causes over 1.8 million deaths a year, making it the world's most deadly human pathogen.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Tanya Parish, Stephen V Gordon

Experts in our system

1
Stephen V. Gordon
University College Dublin
Total Publications: 40