Type

Journal Article

Authors

Glen A Doherty
Juliette Sheridan
Deirdre J Murphy
Kathryn Byrne
Denise Keegan
Hugh E Mulcahy
Garret Cullen
Catherine R Rowan

Subjects

Medicine & Nursing

Topics
cord blood caesarean section gestation clinical pregnancy woman maternal drug

Ustekinumab Drug Levels in Maternal and Cord Blood in a Woman With Crohn's Disease Treated Until 33 Weeks of Gestation. (2017)

Abstract A 35-year old woman with ileocolonic, perianal, and vulval Crohn's disease was treated with subcutaneous ustekinuamb [USK] throughout pregnancy. Dose intervals were shortened from 6-weekly to 4-weekly to maintain clinical remission. The last dose of USK was administered at 33 weeks of gestation, and a healthy baby boy was delivered by caesarean section at 37 weeks. Maternal trough USK levels remained stable during pregnancy. Cord blood USK levels were nearly 2-fold higher than contemporaneous maternal serum levels. To our knowledge, this is the first report of maternal and cord USK levels in a patient with Crohn's disease.
Collections Ireland -> University College Dublin -> PubMed

Full list of authors on original publication

Glen A Doherty, Juliette Sheridan, Deirdre J Murphy, Kathryn Byrne, Denise Keegan, Hugh E Mulcahy, Garret Cullen, Catherine R Rowan

Experts in our system

1
Glen A Doherty
University College Dublin
Total Publications: 57
 
2
Juliette Sheridan
University College Dublin
Total Publications: 7
 
3
Deirdre Murphy
Trinity College Dublin
Total Publications: 34
 
4
Kathryn Byrne
University College Dublin
Total Publications: 16
 
5
Denise Keegan
University College Dublin
Total Publications: 22
 
6
Hugh E Mulcahy
University College Dublin
Total Publications: 43
 
7
Garret Cullen
University College Dublin
Total Publications: 17