Journal Article


John E Fenton
J P O'Neill
P. Lennon


Medicine & Nursing

length of stay patients clinical trials care infectious mononucleosis glandular fever metronidazole randomized controlled trial

Effect of metronidazole versus standard care on length of stay of patients admitted with severe infectious mononucleosis: a randomized controlled trial (2014)

Abstract Metronidazole may be of use in the treatment of infectious mononucleosis (IM). Our aim is to show that metronidazole shortens hospital stay for patients with severe IM. A single-centre randomized controlled trial was undertaken in patients admitted with severe IM, who were with a similar group treated by the standard care. Patients were blinded to which treatment arm they were in. Forty-two of these patients were enrolled in the trial. The primary endpoint was the difference in length of stay. This was significantly less in the metronidazole group (3.67 days v 4.67) (p 0.032). This study demonstrates that metronidazole has a role to play in severe infectious mononucleosis.
Collections Ireland -> University of Limerick -> Graduate Entry Medical School
Ireland -> University of Limerick -> Faculty of Education & Health Sciences
Ireland -> University of Limerick -> Departments Education & Health Sciences

Full list of authors on original publication

John E Fenton, J P O'Neill, P. Lennon

Experts in our system

J E Fenton
University of Limerick
Total Publications: 14
J P O'Neill
Royal College of Surgeons in Ireland
Total Publications: 21