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Type

Journal Article

Authors

Eimear Dunne
Dermot Kenny
Bryan T Hennessy
Antonio J Ricco
Willard Tinago
Niamh Keegan
Roisin Walsh
Louis Richter
Jonathan Cowman

Subjects

Medicine & Nursing

Topics
thromboembolism controls von willebrand factor blood shear flow plate platelet cancer patients

Dynamic platelet function is markedly different in patients with cancer compared to healthy donors. (2018)

Abstract Despite a fivefold increased risk of thromboembolism in patients with cancer, the mechanism of arterial thromboembolism is poorly understood. To address this, we investigated platelet function in cancer patients and healthy controls using an assay that mimics the arterial vasculature. Blood samples from cancer patients (n = 36) and healthy controls (n = 22) were perfused through custom-made parallel-plate flow chambers coated with von Willebrand factor (VWF) under arterial shear (1,500 s
Url http://www.ncbi.nlm.nih.gov/pubmed/30252557
Collections Ireland -> Dublin City University -> PubMed

Full list of authors on original publication

Eimear Dunne, Dermot Kenny, Bryan T Hennessy, Antonio J Ricco, Willard Tinago, Niamh Keegan, Roisin Walsh, Louis Richter, Jonathan Cowman

Experts in our system

1
Eimear Dunne
Royal College of Surgeons in Ireland
Medicine & Nursing Biochemistry
Total Publications: 19
 
2
Dermot Kenny
Royal College of Surgeons in Ireland
Medicine & Nursing Biochemistry Pharmacology
Total Publications: 71
 
3
Bryan T Hennessy
Royal College of Surgeons in Ireland
Medicine & Nursing Biochemistry
Total Publications: 33
 
4
Antonio J. Ricco
Dublin City University
Medicine & Nursing Biochemistry
Total Publications: 24
 
5
Willard Tinago
University College Dublin
Medicine & Nursing
Total Publications: 7
 
6
Jonathan Cowman
Dublin City University
Medicine & Nursing Mathematics
Total Publications: 3