Type

Journal Article

Authors

Declan Walsh
Aileen Kennedy
Norma O'Leary
Stephen Higgins
Lucy Balding
Jessica Sui
Michelle Barrett
Pauline Ui Dhuibhir
Niamh McGettigan

Subjects

Medicine & Nursing

Topics
prevalence smell cancer patients nutritional status cancer taste etiology sensation

Subjective and Objective Assessment of Taste and Smell Sensation in Advanced Cancer. (2019)

Abstract Taste and smell abnormalities (TSA) occur throughout the cancer trajectory regardless of cancer primary site and contribute to cancer-associated malnutrition. TSA etiology is poorly understood. Tumor-related inflammation is a possible cause. This study examined the prevalence, characteristics, and severity of TSA in advanced cancer and explored the relationship between TSA and nutritional status. No previous study combined subjective and objective measures for both taste and smell assessment in this population. Consecutive advanced cancer hospice patients were recruited. A modified version of the "Taste and Smell Survey" assessed subjective TSA. Validated taste strips and "Sniffin' Sticks" were the objective measures. The abridged patient-generated subjective global assessment evaluated nutritional status. A 93% prevalence of TSA in 30 patients with advanced cancer was identified. When subjective and objective evaluations were combined, 28 had taste abnormalities, 24 smell abnormalities, and 24 both. Taste changes included "persistent bad taste" (n = 18) and changes in how basic tastes were perceived. Half reported smell was not "as strong" as prediagnosis, while more than half (n = 16) had an objective smell abnormality. Most (97%) were at risk of malnutrition. Fatigue, dry mouth, early satiety, and anorexia were common nutrition-impact symptoms. No statistically significant relationship was found between TSA and malnutrition scores. TSA were highly prevalent. Subjective taste and smell changes did not always accord with objective TSA, suggesting both assessments are valuable. TSA characteristics varied, and particular foods tasted and smelled different and were not enjoyed as before. TSA are common, high-impact problems in advanced cancer.
Collections Ireland -> Dublin Institute of Technology -> PubMed

Full list of authors on original publication

Declan Walsh, Aileen Kennedy, Norma O'Leary, Stephen Higgins, Lucy Balding, Jessica Sui, Michelle Barrett, Pauline Ui Dhuibhir, Niamh McGettigan

Experts in our system

1
Declan Walsh
Trinity College Dublin
Total Publications: 7
 
2
Aileen Kennedy
Dublin City University
Total Publications: 32
 
3
Pauline Ui Dhuibhir
Trinity College Dublin
Total Publications: 3