Type

PhD Thesis

Authors

Anne Nugent

Subjects

Agriculture & Food Science

Topics
ph d trinity college dublin clinical medicine ph d immune system conjugated linoleic acid polyunsaturated fatty acids dairy products linoleic acid dietary acids

The effects of conjugated linoleic acid on the human immune system (2003)

Abstract The cells of the immune system are sensitive to their exogenous environment. Indeed the amount and type of nutrients, including fatty acids, which this environmentcontains all influence subsequent immune cell functioning. Dietary fatty acids, in particular polyunsaturated fatty acids, modulate immune function. However, less is known about the effects of the dietary fatty acid conjugated linoleic acid (CLA) on immune function. CLA is a mix of positional and geometric isomers of the fatty acid linoleic acid. The predominant isomers are a cis-9, trans-11 CLA and trans-10, cis -12 CLA. Although it can be synthesised industrially, natural dietary sources include dairy products and certain meats (e.g. lamb). This thesis aims to investigate the influence of these two CLA isomers onhuman immune function ex vivo and in vitro and to investigate the molecular m echanismsunderlying their effects.
Collections Ireland -> Trinity College Dublin -> Clinical Medicine (Theses and Dissertations)
Ireland -> Trinity College Dublin -> Clinical Medicine
Ireland -> Trinity College Dublin -> Trinity College Dublin Theses & Dissertations
Ireland -> Trinity College Dublin -> Trinity College Dublin, the University of Dublin: Theses & Dissertations
Ireland -> Trinity College Dublin -> School of Medicine

Full list of authors on original publication

Anne Nugent

Experts in our system

1
Anne P Nugent
University College Cork