Type

Journal Article

Authors

Douwe van Sinderen
Viktor Boer
Tadhg O'Sullivan
Jean-Paul Noben
Charles M. A. P. Franz
Horst Neve
Jennifer Mahony
Marine Feyereisen

Subjects

Agriculture & Food Science

Topics
lactic acid bacteria genomic analysis beer spoilage prophage induction lysogeny bacteriophage myoviridae

Biodiversity and classification of phages infecting Lactobacillus brevis (2019)

Abstract Lactobacillus brevis is a lactic acid bacterium that is known as a food and beverage spoilage organism, and more specifically as a beer-spoiler. Phages of L. brevis have been described, but very limited data is available regarding temperate phages of L. brevis. Temperate phages may exert benefits to the host, while they may also be employed to combat beer spoilage. The current study reports on the incidence of prophage sequences present in nineteen distinct L. brevis genomes. Prophage induction was evaluated using mitomycin C exposure followed by genome targeted-PCR, electron microscopy and structural proteome analysis. The morphological and genome sequence analyses revealed significant diversity among L. brevis prophages, which appear to be dominated by members of the Myoviridae phage family. Based on this analysis, we propose a classification of L. brevis phages into five groups.
Collections Ireland -> University College Cork -> APC Microbiome Institute
Ireland -> University College Cork -> College of Science, Engineering and Food Science
Ireland -> University College Cork -> APC Microbiome Institute- Journal Articles
Ireland -> University College Cork -> Microbiology
Ireland -> University College Cork -> Research Institutes and Centres
Ireland -> University College Cork -> Microbiology - Journal Articles

Full list of authors on original publication

Douwe van Sinderen, Viktor Boer, Tadhg O'Sullivan, Jean-Paul Noben, Charles M. A. P. Franz, Horst Neve, Jennifer Mahony, Marine Feyereisen

Experts in our system

1
Douwe van Sinderen
University College Cork
Total Publications: 144
 
2
Tadhg O'Sullivan
University College Cork
Total Publications: 7
 
3
Jean-Paul Noben
University College Cork
Total Publications: 13
 
4
Charles M. A. P. Franz
University College Cork
 
5
Horst Neve
University College Cork
Total Publications: 41
 
6
Jennifer Mahony
University College Cork
Total Publications: 87
 
7
Marine Feyereisen
University College Cork
Total Publications: 6