Type

Journal Article

Authors

Peadar G Lawlor
Gillian E Gardiner
Orla O'Sullivan
Paul D. Cotter
Fiona Crispie
Natalie Rebeiz
Michael Harrison
Stefan G Buzoianu
Maria L Prieto
Henry Reyer
and 5 others

Subjects

Agriculture & Food Science

Topics
geographic location northern ireland intestinal microbiota health status feed efficiency fatty acids volatile pigs feed intake

Porcine feed efficiency-associated intestinal microbiota and physiological traits: finding consistent cross-locational biomarkers for residual feed intake (2019)

Abstract Optimal feed efficiency (FE) in pigs is important for economic and environmental reasons. Previous research identified FE-associated bacterial taxa within the intestinal microbiota of growing pigs. This study investigated whether FE-associated bacteria and selected FE-associated physiological traits were consistent across geographic locations (Republic of Ireland [ROI] [two batches of pigs, ROI1 and ROI2], Northern Ireland [NI], and Austria [AT]), where differences in genetic, dietary, and management factors were minimized. Pigs (n = 369) were ranked, within litter, on divergence in residual feed intake (RFI), and 100 extremes were selected (50 with high RFI and 50 with low RFI) across geographic locations for intestinal microbiota analysis using 16S rRNA amplicon sequencing and examination of FE-associated physiological parameters. Microbial diversity varied by geographic location and intestinal sampling site but not by RFI rank, except in ROI2, where more-feed-efficient pigs had greater ileal and cecal diversity. Although none of the 188 RFI-associated taxonomic differences found were common to all locations/batches, Lentisphaerae, Ruminococcaceae, RF16, Mucispirillum, Methanobrevibacter, and two uncultured genera were more abundant within the fecal or cecal microbiota of low-RFI pigs in two geographic locations and/or in both ROI batches. These are major contributors to carbohydrate metabolism, which was reflected in functional predictions. Fecal volatile fatty acids and salivary cortisol were the only physiological parameters that differed between RFI ranks. Despite controlling genetics, diet specification, dietary phases, and management practices in each rearing environment, the rearing environment, encompassing maternal influence, herd health status, as well as other factors, appears to impact intestinal microbiota more than FE.IMPORTANCE Interest in the role of intestinal microbiota in determining FE in pigs has increased in recent years. However, it is not known if the same FE-associated bacteria are found across different rearing environments. In this study, geographic location and intestinal sampling site had a greater influence on the pig gut microbiome than FE. This presents challenges when aiming to identify consistent reliable microbial biomarkers for FE. Nonetheless, seven FE-associated microbial taxa were common across two geographic locations and/or two batches within one location, and these indicated a potentially “healthier” and metabolically more capable microbiota in more-feed-efficient pigs. These taxa could potentially be employed as biomarkers for FE, although bacterial consortia, rather than individual taxa, may be more likely to predict FE. They may also merit consideration for use as probiotics or could be targeted by dietary means as a strategy for improving FE in pigs in the future.
Collections Ireland -> University College Cork -> APC Microbiome Institute
Ireland -> University College Cork -> College of Science, Engineering and Food Science
Ireland -> University College Cork -> APC Microbiome Institute- Journal Articles
Ireland -> University College Cork -> Microbiology
Ireland -> University College Cork -> Research Institutes and Centres
Ireland -> University College Cork -> Microbiology - Journal Articles

Full list of authors on original publication

Peadar G Lawlor, Gillian E Gardiner, Orla O'Sullivan, Paul D. Cotter, Fiona Crispie, Natalie Rebeiz, Michael Harrison, Stefan G Buzoianu, Maria L Prieto, Henry Reyer and 5 others

Experts in our system

2
Gillian E. Gardiner
Teagasc
Total Publications: 63
 
3
Orla O'Sullivan
Teagasc
Total Publications: 103
 
4
Paul D. Cotter
Teagasc
Total Publications: 296
 
5
Fiona Crispie
Teagasc
Total Publications: 40
 
6
Michael Harrison
Waterford Institute of Technology
Total Publications: 36
 
7
Stefan G. Buzoianu
Teagasc
Total Publications: 14
 
8
Henry Reyer
Teagasc
Total Publications: 7