Type

Journal Article

Authors

Douwe van Sinderen
Tadhg O'Sullivan
Jean-Paul Noben
Charles M. A. P. Franz
Horst Neve
Marco Ventura
Gabriele A. Lugli
Jennifer Mahony
Marine Feyereisen

Subjects

Agriculture & Food Science

Topics
fermentation food preservation virulent lactobacillus brevis genomic and proteomic analysis bacteriophage beer isolation

Isolation and characterization of Lactobacillus brevis phages (2019)

Abstract Lactobacillus brevis has been widely used in industry for fermentation purposes. However, it is also associated with the spoilage of foods and beverages, in particular, beer. There is an increasing demand for natural food preservation methods, and in this context, bacteriophages possess the potential to control such spoilage bacteria. Just a few studies on phages infecting Lactobacillus brevis have been performed to date and in the present study, we report the isolation and characterization of five virulent phages capable of infecting Lb. brevis strains. The analysis reveals a high diversity among the isolates, with members belonging to both, the Myoviridae and Siphoviridae families. One isolate, designated phage 3-521, possesses a genome of 140.8 kb, thus representing the largest Lb. brevis phage genome sequenced to date. While the isolated phages do not propagate on Lb. brevis beer-spoiling strains, phages showed activity against these strains, impairing the growth of some Lb. brevis strains. The results highlight the potential of bacteriophage-based treatments as an effective approach to prevent bacterial spoilage of beer.
Collections Ireland -> University College Cork -> APC Microbiome Institute
Ireland -> University College Cork -> College of Science, Engineering and Food Science
Ireland -> University College Cork -> APC Microbiome Institute- Journal Articles
Ireland -> University College Cork -> Microbiology
Ireland -> University College Cork -> Research Institutes and Centres
Ireland -> University College Cork -> Microbiology - Journal Articles

Full list of authors on original publication

Douwe van Sinderen, Tadhg O'Sullivan, Jean-Paul Noben, Charles M. A. P. Franz, Horst Neve, Marco Ventura, Gabriele A. Lugli, Jennifer Mahony, Marine Feyereisen

Experts in our system

1
Douwe van Sinderen
University College Cork
Total Publications: 144
 
2
Tadhg O'Sullivan
University College Cork
Total Publications: 7
 
3
Jean-Paul Noben
University College Cork
Total Publications: 13
 
4
Charles M. A. P. Franz
University College Cork
 
5
Horst Neve
University College Cork
Total Publications: 41
 
6
Marco Ventura
University College Cork
Total Publications: 52
 
7
Gabriele Andrea Lugli
University College Cork
Total Publications: 35
 
8
Jennifer Mahony
University College Cork
Total Publications: 87
 
9
Marine Feyereisen
University College Cork
Total Publications: 6