Type

Journal Article

Authors

Michael Gill
Suzannah Philips
Robert Heaton
Iain Hargreaves
Christina Mooney
Áine Maguire
April Hargreaves

Subjects

Psychiatry

Topics
bipolar disorder ra790 mental health psychology oxidative stress cognitive psychology fatigue syndrome chronic double blind co enzyme q10

Effectiveness of orally administered co-enzyme Q10 for schizophrenia: cognitive, functional and biochemical outcomes from a double blind, randomised, placebo controlled trial (2020)

Abstract Coenzyme Q10 (CoQ10) is an endogenous compound that is essential for energy production within the mitochondria and also functions as a potent anti-oxidant, inhibiting oxidative stress and damage. Often deficits in CoQ10 are associated with fatigue, and cognitive and psychological impairment. In light of its many functions, CoQ10 supplementation to minimise decline and improve symptoms has been investigated in multiple disorders including neurological and neuropsychiatric disorders, with results indicating positive effects on fatigue, cognitive impairment and affective difficulties for disorders such as bipolar disorder and chronic fatigue syndrome. There is also evidence of mitochondrial dysfunction in schizophrenia. In light of this evidence, the current study aimed to investigate the potential effect of CoQ10 supplementation on 1) cognitive function and 2) psychological and physical health in schizophrenia and schizoaffective disorder.
Collections Ireland -> National College Ireland -> Status = Published
Ireland -> National College Ireland -> Subject = B Philosophy. Psychology. Religion: Psychology: Cognitive psychology
Ireland -> National College Ireland -> Subject = B Philosophy. Psychology. Religion
Ireland -> National College Ireland -> Subject = R Medicine: RA Public aspects of medicine: RA790 Mental Health
Ireland -> National College Ireland -> Subject = R Medicine
Ireland -> National College Ireland -> Type = Article
Ireland -> National College Ireland -> Subject = B Philosophy. Psychology. Religion: Psychology
Ireland -> National College Ireland -> Subject = R Medicine: RA Public aspects of medicine

Full list of authors on original publication

Michael Gill, Suzannah Philips, Robert Heaton, Iain Hargreaves, Christina Mooney, Áine Maguire, April Hargreaves

Experts in our system

1
Michael Gill
Trinity College Dublin
Total Publications: 294
 
2
Áine Maguire
National College Ireland
Total Publications: 6
 
3
April Hargreaves
National College Ireland
Total Publications: 39