Type

Journal Article

Authors

Michael Gilchrist
Michel Destrade
Badar Rashid

Subjects

Engineering

Topics
friction tissue lubricant specimen computational approach stress mechanical determination environment controlled lubrication swine strain rates computational friction coefficient ogden animals bonded platen biomechanical phenomena brain mechanical properties compressive strength cytology brain tissue compression materials testing

Determination of friction coefficient in unconfined compression of brain tissue (2012)

Abstract Unconfined compression tests are more convenient to perform on cylindrical samples of brain tissue than tensile tests in order to estimate mechanical properties of the brain tissue because they allow for homogeneous deformations. The reliability of these tests depends significantly on the amount of friction generated at the specimen/platen interface. Thus, there is a crucial need to find an approximate value of the friction coefficient in order to predict a possible overestimation of stresses during unconfined compression tests. In this study, a combined experimental-computational approach was adopted to estimate the dynamic friction coefficient mu of porcine brain matter against metal platens in compressive tests. Cylindrical samples of porcine brain tissue were tested up to 30% strain at variable strain rates, both under bonded and lubricated conditions in the same controlled environment. It was established that mu was equal to 0.09 +/- 0.03, 0.18 +/- 0.04, 0.18 +/- 0.04 and 0.20 +/- 0.02 at strain rates of 1, 30, 60 and 90/s, respectively. Additional tests were also performed to analyze brain tissue under lubricated and bonded conditions, with and without initial contact of the top platen with the brain tissue, with different specimen aspect ratios and with different lubricants (Phosphate Buffer Saline (PBS), Polytetrafluoroethylene (PTFE) and Silicon). The test conditions (lubricant used, biological tissue, loading velocity) adopted in this study were similar to the studies conducted by other research groups. This study will help to understand the amount of friction generated during unconfined compression of brain tissue for strain rates of up to 90/s.
Collections Ireland -> National University of Ireland Galway -> Mathematics
Ireland -> National University of Ireland Galway -> School of Mathematics, Statistics and Applied Mathematics
Ireland -> University College Dublin -> Mechanical & Materials Engineering Research Collection
Ireland -> National University of Ireland Galway -> Mathematics (Scholarly Articles)
Ireland -> National University of Ireland Galway -> College of Science
Ireland -> University College Dublin -> College of Engineering & Architecture
Ireland -> University College Dublin -> School of Mechanical and Materials Engineering

Full list of authors on original publication

Michael Gilchrist, Michel Destrade, Badar Rashid

Experts in our system

1
M. D. Gilchrist
University College Dublin
Total Publications: 172
 
2
Michel Destrade
National University of Ireland Galway
Total Publications: 106
 
3
Badar Rashid
University College Dublin
Total Publications: 16