Type

Journal Article

Authors

Stephen V. Gordon
Adam Witney
Javier Nunez
Paul Golby

Subjects

Veterinary

Topics
gene expression macrophage microarray mycobacterium bovis antisense bovine tuberculosis transcript snp

Genome-level analyses of Mycobacterium bovis lineages reveal the role of SNPs and antisense transcription in differential gene expression (2013)

Abstract Bovine tuberculosis (bTB) is a disease with major implications for animal welfare and productivity, as well as having the potential for zoonotic transmission. In Great Britain (GB) alone, controlling bTB costs in the region of £100 million annually, with the current control scheme seemingly unable to stop the inexorable spread of infection. One aspect that may be driving the epidemic is evolution of the causative pathogen, Mycobacterium bovis. To understand the underlying genetic changes that may be responsible for this evolution, we performed a comprehensive genome-level analyses of 4 M. bovis strains that encompass the main molecular types of the pathogen circulating in GB.
Collections Ireland -> University College Dublin -> Veterinary Medicine Research Collection (superseded in 2015)
Ireland -> University College Dublin -> College of Agriculture, Food Science and Veterinary Medicine (superseded in 2015)
Ireland -> University College Dublin -> School of Veterinary Medicine (superseded in 2015)

Full list of authors on original publication

Stephen V. Gordon, Adam Witney, Javier Nunez, Paul Golby

Experts in our system

1
Stephen V. Gordon
University College Dublin
Total Publications: 40