Journal Article


Mark Crowe
P. Duffy
M. J. Canty
S. W. Walsh
Marijke Eileen Beltman



ovarian cysts ovarian follicle physiopathology composition insulin like growth factor binding proteins veterinary pathogenesis hormones insulin like growth factor i mare metabolism structures binding follicular fluid female chemistry abnormal follicles progesterone higher horse diseases igf hormonal oestradiol animals horses

Hormonal composition of follicular fluid from abnormal follicular structures in mares (2014)

Abstract The objective was to characterise the hormonal composition of follicular fluid from mares with distinct anovulatory-cystic follicles. Follicular fluid was aspirated from six mares that presented with cystic follicles and from pre-ovulatory follicles of five normal mares (controls). Differences in progesterone, oestradiol, testosterone, IGF-I and IGF binding were analysed using Fisher's exact test. There were greater (P<0.03) follicular fluid oestradiol concentrations in normal follicles and the testosterone concentration of the cystic fluid was greater (P<0.05) than that of the normal fluid. There also was a greater (P<0.03) percentage of IGF-I binding and lower (P<0.02) IGF-I concentrations in the fluid collected from the cystic structures compared with the fluid from normal follicles. Despite the limited number of animals, the fact that fluid aspirated from cystic follicles had higher testosterone and lower oestradiol concentrations could be of diagnostic value when a practitioner wants to distinguish between a cystic and non-cystic persistent follicle. The research reported here also indicates a likely role for the IGF system in the pathogenesis of the development and maintenance of anovulatory follicular structures in mare ovaries.
Collections Ireland -> University College Dublin -> Veterinary Medicine Research Collection (superseded in 2015)
Ireland -> University College Dublin -> College of Agriculture, Food Science and Veterinary Medicine (superseded in 2015)
Ireland -> University College Dublin -> School of Veterinary Medicine (superseded in 2015)

Full list of authors on original publication

Mark Crowe, P. Duffy, M. J. Canty, S. W. Walsh, Marijke Eileen Beltman

Experts in our system

M A Crowe
Total Publications: 102
P. Duffy
University College Dublin
Total Publications: 42
Mary J Canty
University College Dublin
S. W. Walsh
Total Publications: 21
Marijke Eileen Beltman
University College Dublin
Total Publications: 24