Type

Journal Article

Authors

Torres Sweeney
John O'Doherty
Petrina Reilly
Tanya Englishby
Deirdre P Campion
Alistair D Black
Bernadette Earley
Aidan P Moloney
Frank J Monahan
Alexandre Lejeune

Subjects

Veterinary

Topics
health status stem cell pasture based human health mrna expression peripheral immune parameters cattle production systems interleukin 4

Peripheral and gastrointestinal immune systems of healthy cattle raised outdoors at pasture or indoors on a concentrate-based ration (2010)

Abstract Background: Despite an increasing preference of consumers for beef produced from more extensive pasture-based production systems and potential human health benefits from the consumption of such beef, data regarding the health status of animals raised on pasture are limited. The objective of this study was to characterise specific aspects of the bovine peripheral and the gastrointestinal muscosal immune systems of cattle raised on an outdoor pasture system in comparison to animals raised on a conventional intensive indoor concentrate-based system. Results: A number of in vitro functional tests of immune cells suggested subtle differences between the animals on the outdoor versus indoor production systems. There was a decrease in the number of neutrophils and monocytes engaged in phagocytosis in outdoor cattle (P < 0.01 and P < 0.05, respectively) in comparison to those indoors. Following mitogen stimulation, a lower level of interferon-γ was produced in leukocytes from the outdoor animals (P < 0.05). There was evidence of a gastrointestinal nematode infection in the outdoor animals with elevated levels of serum pepsinogen (P < 0.001), a higher number of eosinophils (P < 0.05) and a higher level of interleukin-4 and stem cell factor mRNA expression (P < 0.05) in the outdoor animals in comparison to the indoor animals. Lower levels of copper and iodine were measured in the outdoor animals in comparison to indoor animals (P < 0.001). Conclusion: Despite distinctly contrasting production systems, only subtle differences were identified in the peripheral immune parameters measured between cattle raised at pasture in comparison to animals raised on a conventional intensive indoor concentrate-based production system.
Collections Ireland -> Teagasc -> Other Teagasc Research
Ireland -> Teagasc -> Animal & Bioscience
Ireland -> Teagasc -> Teagasc publications in Biomed Central
Ireland -> Teagasc -> Animal & Grassland Research & Innovation Programme

Full list of authors on original publication

Torres Sweeney, John O'Doherty, Petrina Reilly, Tanya Englishby, Deirdre P Campion, Alistair D Black, Bernadette Earley, Aidan P Moloney, Frank J Monahan, Alexandre Lejeune

Experts in our system

1
T Sweeney
University College Dublin
Total Publications: 138
 
2
J V O'Doherty
University College Dublin
Total Publications: 96
 
3
Deirdre P. Campion
University College Dublin
Total Publications: 16
 
4
Bernadette Earley
Teagasc
Total Publications: 120
 
5
A P Moloney
Teagasc
Total Publications: 101
 
6
F.J. Monahan
University College Dublin
Total Publications: 71