Type

Journal Article

Authors

Stephen T. Butler
A.C.O. Evans
P. Lonergan
Richard J. Dewhurst
Catherine Stanton
Michael J. de Veth
Ian A. Hutchinson

Subjects

Veterinary

Topics
female chemistry cattle pregnancy dry matter intake energy balance animal feed conjugated linoleic acid conjugated linoleic acid cla insulin like growth factor i pharmacology animal nutritional physiological phenomena milk animals lipids fatty acids diet linoleic acids conjugated administration dosage veterinary reproduction energy metabolism dietary supplements milk fat dairying lactation dairy cows drug effects

Effects of lipid-encapsulated conjugated linoleic acid supplementation on milk production, bioenergetic status and indicators of reproductive performance in lactating dairy cows (2011)

Abstract Conjugated linoleic acid (CLA) reduces mammary milk fat synthesis in a dose-dependent manner. Our objective was to determine the effects of lipid-encapsulated CLA (LE-CLA) supplementation on milk production, reproductive performance and metabolic responses in lactating dairy cows fed a grass silage-based diet. Seventy-two Holstein-Friesian cows (32 primiparous and 40 multiparous) were used in a completely randomized block design. Cows received either 80 g of LE-CLA daily or 60 g of calcium salts of palm fatty acids daily (control) from parturition until 60 days in milk. LE-CLA contained a 50:50 mix of cis-9,trans-11 CLA and trans-10,cis-12 CLA, resulting in a daily intake of 6 g of each isomer. Milk production and dry matter intake were recorded daily, and blood samples were collected 3-times a week. Blood samples were analysed for circulating concentrations of glucose, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHBA), insulin and insulin-like growth factor-I (IGF-I). Progesterone was measured in blood samples collected after the first post-partum insemination. Ovarian ultrasound examinations commenced at 8–10 d post partum and were carried out 3-times a week until first ovulation. LE-CLA treatment resulted in decreased milk fat concentration, with consequent improvements in energy balance and body condition score (BCS). The peak concentration of NEFA in blood was reduced by LE-CLA, but circulating concentrations of insulin, glucose, IGF-I, BHBA and progesterone were not affected. There was no effect of LE-CLA supplementation on the post-partum interval to first ovulation. Services per conception tended to be reduced. The reduction in milk energy output and improvement in energy status and BCS in LE-CLA-supplemented cows provides a strong rationale for further studies with greater cow numbers to test effects on reproductive performance.
Collections Ireland -> Teagasc -> Food Biosciences
Ireland -> Teagasc -> Animal & Bioscience
Ireland -> Teagasc -> Animal & Grassland Research & Innovation Programme
Ireland -> Teagasc -> Food Programme

Full list of authors on original publication

Stephen T. Butler, A.C.O. Evans, P. Lonergan, Richard J. Dewhurst, Catherine Stanton, Michael J. de Veth, Ian A. Hutchinson

Experts in our system

1
S T Butler
Teagasc
Total Publications: 81
 
2
A.C.O. Evans
University College Dublin
Total Publications: 92
 
3
P. Lonergan
University College Dublin
Total Publications: 190
 
4
Richard J. Dewhurst
Teagasc
Total Publications: 10
 
5
Catherine Stanton
Teagasc
Total Publications: 267
 
6
I A Hutchinson
Teagasc
Total Publications: 10