Type

Journal Article

Authors

William J Meaney
Colin Hill
R Paul Ross
James Flynn
Fiona Crispie

Subjects

Microbiology

Topics
teat seal formulation intramammary teat seal bismuth combination therapy novel the lacticin 3147 cow lactococcus lactis intramammary infections

Update on the development of a novel dry cow therapy using a bismuth-based intramammary teat seal in combination with the bacteriocin lacticin 3147 (2004)

Abstract Public concerns over the widespread prophylactic use of antibiotics have led to a search for alternatives to dry cow therapy for the prevention of intramammary infections. A popular alternative is to infuse a teat seal at drying-off. The teat seal is a viscous non-antibiotic formulation and when it is infused into the teat canal and the teat sinus it forms an internal seal that provides a physical barrier to invasion by mastitis-causing pathogens. Enhancement of teat seal formulations may be achieved using non-antibiotic additives such as bacteriocins, potent proteins produced by some bacteria that have the ability to kill other microorganisms. This paper traces the history of investigations at Moorepark Research Centre into the efficacy of teat seal plus lacticin 3147, a bacteriocin produced by Lactococcus lactis DPC3147, in the prevention of intramammary infections in dry cows. Indications from on-going investigations are that a dry cow formulation combining the two products has considerable potential as a non-antibiotic prophylactic product.
Collections Ireland -> Teagasc -> Other Teagasc Research
Ireland -> Teagasc -> Teagasc publications in Biomed Central

Full list of authors on original publication

William J Meaney, Colin Hill, R Paul Ross, James Flynn, Fiona Crispie

Experts in our system

1
Colin Hill
University College Cork
Total Publications: 351
 
2
R Paul Ross
Teagasc
Total Publications: 441
 
3
James Flynn
Teagasc
Total Publications: 15
 
4
Fiona Crispie
Teagasc
Total Publications: 30