Type

Journal Article

Authors

Sumsun Naher
Dermot Brabazon
Farah Naz Talpur
Tasneem Gul Kazi
Farah Naz Talpur
Hassan Imran Afridi
Tasneem Gul Kazi

Subjects

Chemistry

Topics
hypertension humans different brands of cigarette nickel chemistry cigarette smokers inductive coupled plasma atomic emission spectrophotometer scalp hair analytical chemistry toxic elements blood hair cadmium smoking lead tobacco adverse effects ireland inductively coupled plasma

Estimation of toxic elements in the samples of different cigarettes and their impact on human health of Irish hypertensive consumers (2013)

Abstract Background: Cigarette smoking interferes with the metal homeostasis of the human body, which plays a crucial role for maintaining the health. A significant flux of heavy metals, among other toxins, reaches the lungs through smoking. In the present study, the relationship between toxic element (TE) exposure via cigarette smoking and hypertension incidence in population living in Dublin, Ireland is investigated. Methods: The different brands of cigarette (filler tobacco, filter and ash) consumed by the studied population were analyzed for cadmium (Cd), nickel (Ni), and lead (Pb). The concentrations of TEs in biological samples and different components of cigarette were measured by inductively coupled plasma atomic emission spectrophotometer after microwave-assisted acid digestion. The validity and accuracy of the methodology were checked using certified reference materials. Results: The filler tobacco of different branded cigarettes contains Cd, Ni and Pb concentrations in the ranges of 1.73-2.02, 0.715-1.52 and 0378-1.16 pg/cigarette, respectively. The results of this study showed that the mean values of Cd, Ni and Pb were significantly higher in scalp hair and blood samples of hypertensive patients in relation to healthy controls, while the difference was significant in the case of smoker patients (p < 0.001). The levels of all the three TEs were 2-3 folds higher in scalp hair and blood samples of non-hypertensive smoker subjects as compared to nonsmoker controls. Conclusion: The high exposure of toxic metals as a result of cigarette smoking may be synergistic with risk factors associated with hypertension.
Collections Ireland -> Dublin City University -> Subject = Physical Sciences: Analytical chemistry
Ireland -> Dublin City University -> Publication Type = Article
Ireland -> Dublin City University -> DCU Faculties and Centres = DCU Faculties and Schools
Ireland -> Dublin City University -> Status = Published
Ireland -> Dublin City University -> DCU Faculties and Centres = DCU Faculties and Schools: Faculty of Engineering and Computing: School of Mechanical and Manufacturing Engineering
Ireland -> Dublin City University -> Subject = Physical Sciences
Ireland -> Dublin City University -> DCU Faculties and Centres = DCU Faculties and Schools: Faculty of Engineering and Computing

Full list of authors on original publication

Sumsun Naher, Dermot Brabazon, Farah Naz Talpur, Tasneem Gul Kazi, Farah Naz Talpur, Hassan Imran Afridi, Tasneem Gul Kazi

Experts in our system

1
Sumsun Naher
Dublin City University
Total Publications: 56
 
2
Dermot Brabazon
Dublin City University
Total Publications: 162