Type

Journal Article

Authors

Lisa Looney
Stefan Lohfeld
Dermot Brabazon
Szilvia Eosoly

Subjects

Engineering

Topics
caprolactone caproates hard tissue engineering lactones chemistry hydroxyapatites selective laser sintering lasers

Selective laser sintering of hydroxyapatite/poly-epsilon-caprolactone scaffolds. (2009)

Abstract Selective laser sintering (SLS) enables the fabrication of complex geometries with the intricate and controllable internal architecture required in the field of tissue engineering. In this study hydroxyapatite and poly-epsilon-caprolactone, considered suitable for hard tissue engineering purposes, were used in a weight ratio of 30:70. The quality of the fabricated parts is influenced by various process parameters. Among them Four parameters, namely laser fill power, outline laser power, scan spacing and part orientation, were identified as important. These parameters were investigated according to a central composite design and a model of the effects of these parameters on the accuracy and mechanical properties of the fabricated parts was developed. The dimensions of the fabricated parts were strongly dependent on the manufacturing direction and scan spacing. Repeatability analysis shows that the fabricated features can be well reproduced. However, there were deviations from the nominal dimensions, with the features being larger than those designed. The compressive modulus and yield strength of the fabricated microstructures with a designed relative density of 0.33 varied between 0.6 and 2.3 and 0.1 and 0.6 MPa, respectively. The mechanical behavior was strongly dependent on the manufacturing direction.
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Full list of authors on original publication

Lisa Looney, Stefan Lohfeld, Dermot Brabazon, Szilvia Eosoly

Experts in our system

1
Lisa Looney
Dublin City University
Total Publications: 10
 
2
Dermot Brabazon
Dublin City University
Total Publications: 162