Journal Article


R O'Kennedy
C O Fágáin
F Manning



von willebrand factor factor structure factor analysis deficiency genetic blood coagulation factor viii diagnostic applications

Factor VIII: structure, function and analysis. (1993)

Abstract Factor VIII is an important blood coagulation protein whose genetic deficiency leads to the serious bleeding disorder, classic haemophilia (haemophilia A). Here we review the structure, function and analysis of this protein for diagnostic and therapeutic applications. Because factor VIII is tightly associated with von Willebrand factor some recent work on the latter is also considered so as to clarify the relationship between them.
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Full list of authors on original publication

R O'Kennedy, C O Fágáin, F Manning

Experts in our system

R O'Kennedy
Dublin City University
Total Publications: 211