Type

Other / n/a

Authors

Maria Santos-Martinez
Carlos Medina Martin
Marek Radomski

Subjects

Chemistry

Topics
novel targets new technologies quasi static nanoscience materials therapeutic targets platelet aggregation platelets microfluidics

Analysis of platelet function: role of microfluidics and nanodevices (2011)

Abstract Platelet aggregation is essential for vascular haemostasis and thrombosis. To improve the therapy of arterial thrombotic disorders and identify novel therapeutic targets it is imperative to study basic mechanisms of platelet thrombus formation. To date most data on biology, physiology and pharmacology of platelet aggregation have been obtained by studying this phenomenon under static or quasi-dynamic conditions at the macroscale level. There is a widespread recognition for the need of new technologies that will help to further elucidate the role of platelets in physiological and pathological thrombus formation and to design more effective and specific antithrombotic drugs. Micro- and nanofluidic devices, capable of reaching nanoscale resolution, can be used for this purpose setting the scene for the development of novel methods for studying platelet function in physiology, pathology and therapeutics.
Collections Ireland -> Trinity College Dublin -> Pharmacy and Pharmaceutical Sciences (Scholarly Publications)
Ireland -> Trinity College Dublin -> Pharmacy and Pharmaceutical Sciences
Ireland -> Trinity College Dublin -> RSS Feeds
Ireland -> Trinity College Dublin -> School of Pharmacy and Pharmaceutical Sciences
Ireland -> Trinity College Dublin -> RSS Feeds

Full list of authors on original publication

Maria Santos-Martinez, Carlos Medina Martin, Marek Radomski

Experts in our system

1
Maria Jose Santos-Martinez
Trinity College Dublin
Total Publications: 29
 
2
Carlos Medina Martin
Trinity College Dublin
Total Publications: 28
 
3
Marek W Radomski
Trinity College Dublin
Total Publications: 44