Journal Article


J Thornton
D J Williams
E Dolan
R Collins
P O'Brien
P O'Kelly
P Brennan
A O'Hare
L Galvin
R Grech
and 5 others



treatment computed tomography national institutes cerebral infarction service acute ischaemic stroke occlusion vessel

Endovascular treatment for acute ischaemic stroke with large vessel occlusion: the experience of a regional stroke service. (2014)

Abstract To report the experience of a regional stroke referral service with endovascular treatment for patients with acute ischaemic stroke (AIS) and large vessel occlusion. A prospective review was undertaken of 93 consecutive cases receiving endovascular treatment for AIS over a 42-month period (January 2010 to June 2013). The National Institutes of Health Stroke Scale (NIHSS), location of large vessel occlusion, details of endovascular procedure, and degree of reperfusion achieved (Thrombolysis In Cerebral Infarction [TICI] score) were recorded. Mortality and functional outcome (modified Rankin Scale [mRS]) were measured at 90 days. The mean patient age was 62 years (range 26-87 years). The mean NIHSS at presentation was 16 (range 6-29). All patients had confirmed proximal large-artery occlusion on computed tomography (CT) angiography: 87 in the anterior circulation, six in the posterior circulation. Of the 93 patients treated, 64 (69%) received intravenous thrombolysis. Successful reperfusion (TICI grade 2a to 3) was achieved in 80 (86%) cases. There were 13 (14%) cases of failed vessel recanalisation (TICI grade 0). Good functional outcome (mRS ≤2) was achieved in 51 (55%) cases. The 90-day mortality was 20 (22%) cases. Fifty-seven (61%) cases were transferred from outside centres. There was no significant increase in morbidity or mortality for transferred patients. Successful endovascular recanalisation can result in good functional outcomes for patients with AIS and large vessel occlusion. Our interventional neuroradiology service provides endovascular treatment as part of a regional stroke service without increase in morbidity or mortality for patients transferred from outside institutions.
Collections Ireland -> IT Blanchardstown -> PubMed

Full list of authors on original publication

J Thornton, D J Williams, E Dolan, R Collins, P O'Brien, P O'Kelly, P Brennan, A O'Hare, L Galvin, R Grech and 5 others

Experts in our system

John Thornton
Royal College of Surgeons in Ireland
Total Publications: 10
David Williams
Royal College of Surgeons in Ireland
Total Publications: 82
Eamon Dolan
IT Blanchardstown
Total Publications: 42
Paul Brennan
Dublin City University
Total Publications: 22