Type

Journal Article

Authors

Marc Devocelle
Hilary Humphreys
Deirdre Fitzgerald-Hughes
Timothy P Smyth
Noel G McElvaney
Catherine Greene
Sally-Ann Cryan
Chandralal M Hewage
Anusha P Subasinghage
Dilip K Rai
and 5 others

Subjects

Microbiology

Topics
medicine and health sciences staphylococcus aureus leukocyte elastase humans pharmacology drug effects peptides cystic fibrosis pseudomonas aeruginosa chemistry medicinal pharmaceutical chemistry genetics microbiology metabolism hemolysis

In vitro activities of synthetic host defense propeptides processed by neutrophil elastase against cystic fibrosis pathogens. (2011)

Abstract The antimicrobial and hemolytic activities of a host defense peptide can be controlled by its modification as a propeptide of reduced net charge, which can then be processed by neutrophil elastase, a serine protease involved in chronic airway inflammation and infections associated with cystic fibrosis.
Collections Ireland -> Royal College of Surgeons in Ireland -> Department of Molecular and Cellular Therapeutics
Ireland -> Royal College of Surgeons in Ireland -> PubMed
Ireland -> Royal College of Surgeons in Ireland -> RCSI Undergraduate Research
Ireland -> Royal College of Surgeons in Ireland -> Molecular and Cellular Therapeutics Articles
Ireland -> Royal College of Surgeons in Ireland -> Department of Medicine
Ireland -> Royal College of Surgeons in Ireland -> School of Pharmacy
Ireland -> Royal College of Surgeons in Ireland -> Clinical Microbiology Articles
Ireland -> Royal College of Surgeons in Ireland -> Department of Clinical Microbiology
Ireland -> Royal College of Surgeons in Ireland -> Medicine Articles
Ireland -> Royal College of Surgeons in Ireland -> Department of Pharmaceutical and Medicinal Chemistry
Ireland -> Royal College of Surgeons in Ireland -> Pharmaceutical and Medicinal Chemistry Articles
Ireland -> Royal College of Surgeons in Ireland -> School of Pharmacy Articles
Ireland -> Royal College of Surgeons in Ireland -> RCSI Undergraduate Research Articles

Full list of authors on original publication

Marc Devocelle, Hilary Humphreys, Deirdre Fitzgerald-Hughes, Timothy P Smyth, Noel G McElvaney, Catherine Greene, Sally-Ann Cryan, Chandralal M Hewage, Anusha P Subasinghage, Dilip K Rai and 5 others

Experts in our system

1
Marc Devocelle
Royal College of Surgeons in Ireland
Total Publications: 65
 
2
Hilary Humphreys
Royal College of Surgeons in Ireland
Total Publications: 142
 
3
Deirdre Fitzgerald-Hughes
Royal College of Surgeons in Ireland
Total Publications: 31
 
4
Noel G McElvaney
Royal College of Surgeons in Ireland
Total Publications: 194
 
5
Catherine M Greene
Royal College of Surgeons in Ireland
Total Publications: 150
 
6
Sally-Ann Cryan
Royal College of Surgeons in Ireland
Total Publications: 70