Type

Journal Article

Authors

Shane J O'Neill
Noel G McElvaney
Tomás P Carroll
Catherine M Greene
Emer Kelly

Subjects

Microbiology

Topics
prognosis genetics risk factors diagnosis complications genotype genetic testing alpha 1 antitrypsin deficiency humans lung diseases phenotype prevalence

Alpha-1 antitrypsin deficiency. (2009)

Abstract To review the topic of alpha-1 antitrypsin (AAT) deficiency. Narrative literature review. Much work has been carried out on this condition with many questions being answered but still further questions remain. AAT deficiency is an autosomal co-dominantly inherited disease which affects the lungs and liver predominantly. The clinical manifestations, prevalence, genetics, molecular pathophysiology, screening and treatment recommendations are summarised in this review.
Collections Ireland -> Royal College of Surgeons in Ireland -> PubMed

Full list of authors on original publication

Shane J O'Neill, Noel G McElvaney, Tomás P Carroll, Catherine M Greene, Emer Kelly

Experts in our system

1
Shane J O'Neill
Royal College of Surgeons in Ireland
Total Publications: 84
 
2
Noel G McElvaney
Royal College of Surgeons in Ireland
Total Publications: 194
 
3
Tomás P Carroll
Royal College of Surgeons in Ireland
Total Publications: 26
 
4
Catherine M Greene
Royal College of Surgeons in Ireland
Total Publications: 150