Type

Journal Article

Authors

Donagh P. Berry
Jennifer McClure
Simon J More
Isabella M Higgins
Dan G Bradley
Ian W Richardson

Subjects

Veterinary

Topics
linear mixed models beef cattle dairy cattle mycobacterium bovis cattle irish tuberculin test irish dairy genetic variation

Variance components for susceptibility to Mycobacterium bovis infection in dairy and beef cattle. (2013)

Abstract Infection of livestock with bovine tuberculosis (bTB; Mycobacterium bovis) is of major economical concern in many countries; approximately 15 000 to 20 000 cattle are infected per year in Ireland. The objective of this study was to quantify the genetic variation for bTB susceptibility in Irish dairy and beef cattle. A total of 105 914 cow, 56 904 heifer and 21 872 steer single intra-dermal comparative tuberculin test records (i.e., binary trait) collected from the years 2001 to 2010 from dairy and beef herds were included in the analysis. Only animal level data pertaining to periods of herd bTB infection were retained. Variance components for bTB were estimated using animal linear and threshold mixed models and co-variances were estimated using sire linear mixed models. Using a linear model, the heritability for susceptibility to bTB in the entire dataset was 0.11 and ranged from 0.08 (heifers in dairy herds) to 0.19 (heifers in beef herds) among the sub-populations investigated. Differences in susceptibility to bTB between breeds were clearly evident. Estimates of genetic correlations for bTB susceptibility between animal types (i.e., cows, heifers, steers) were all positive (0.10 to 0.64), yet different from one. Furthermore, genetic correlations for bTB susceptibility between environments that differed in herd prevalence of bTB ranged from 0.06 to 0.86 and were all different from one. Genetic trends for bTB susceptibility observed in this study suggest a slight increase in genetic susceptibility to bTB in recent years. Since bTB is of economic importance and because all animals are routinely tested at least once annually in Ireland and some other countries, the presence of genetic variation for bTB susceptibility suggests that bTB susceptibility should be included in a national breeding program to halt possible deterioration in genetic susceptibility to bTB infection.
Collections Ireland -> Teagasc -> PubMed

Full list of authors on original publication

Donagh P. Berry, Jennifer McClure, Simon J More, Isabella M Higgins, Dan G Bradley, Ian W Richardson

Experts in our system

1
D P Berry
Teagasc
Total Publications: 215
 
2
Jennifer McClure
Teagasc
Total Publications: 5
 
3
S J More
University College Dublin
Total Publications: 171
 
4
Isabella M. Higgins
Teagasc
Total Publications: 13
 
5
Ian W. Richardson
Teagasc
Total Publications: 8