Type

Journal Article

Authors

Colin Hill
R Paul Ross
Paul D. Cotter

Subjects

Chemistry

Topics
traditional resistance probiotic bacteria spectra bacteriocins antibiotics antimicrobial peptides alternative

Bacteriocins - a viable alternative to antibiotics? (2012)

Abstract Solutions are urgently required for the growing number of infections caused by antibiotic-resistant bacteria. Bacteriocins, which are antimicrobial peptides produced by certain bacteria, might warrant serious consideration as alternatives to traditional antibiotics. These molecules exhibit significant potency against other bacteria (including antibiotic-resistant strains), are stable and can have narrow or broad activity spectra. Bacteriocins can even be produced in situ in the gut by probiotic bacteria to combat intestinal infections. Although the application of specific bacteriocins might be curtailed by the development of resistance, an understanding of the mechanisms by which such resistance could emerge will enable researchers to develop strategies to minimize this potential problem.
Collections Ireland -> Teagasc -> PubMed

Full list of authors on original publication

Colin Hill, R Paul Ross, Paul D. Cotter

Experts in our system

1
Colin Hill
University College Cork
Total Publications: 351
 
2
R Paul Ross
Teagasc
Total Publications: 441
 
3
Paul D. Cotter
Teagasc
Total Publications: 253