Journal Article


Ron Pinhasi
Daniel G Bradley
Michael Hofreiter
Thomas F G Higham
Pál Raczky
János Dani
Alasdair Whittle
Alexandra Anders
Ildikó Pap
Ivett Kővári
and 7 others



prehistory human genome iron age influence millennium dna european

Genome flux and stasis in a five millennium transect of European prehistory. (2014)

Abstract The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (~22 × ) and seven to ~1 × coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence.
Collections Ireland -> Trinity College Dublin -> PubMed

Full list of authors on original publication

Ron Pinhasi, Daniel G Bradley, Michael Hofreiter, Thomas F G Higham, Pál Raczky, János Dani, Alasdair Whittle, Alexandra Anders, Ildikó Pap, Ivett Kővári and 7 others

Experts in our system

Ron Pinhasi
University College Dublin
Total Publications: 47
Daniel Bradley
Trinity College Dublin
Total Publications: 84
Michael Hofreiter
Trinity College Dublin
Total Publications: 12
Thomas F G Higham
Trinity College Dublin
Total Publications: 8