Journal Article


H Z Zhang
J J Boland
C Reid
G Behan
D Bazou



caco 2 cells specimen handling ultrastructure microscopy electron scanning humans epithelial cells cytological techniques

Imaging of human colon cancer cells using He-Ion scanning microscopy. (2010)

Abstract Due to its low beam current and charge compensation mechanism He-Ion scanning microscopy is a very promising tool for imaging biological cells. However, to obtain relevant information, the method used for sample preparation is also critical. In this work, we have used a Carl Zeiss Orion Plus helium-ion microscope to study the effect of sample gold coating on the morphology of human colorectal adenocarcinoma Caco2 cells. The fixative glutaraldehyde was used and the selective gold coating of the samples was investigated. A comparative study with standard scanning electron microscopy is presented.
Collections Ireland -> Trinity College Dublin -> PubMed

Full list of authors on original publication

H Z Zhang, J J Boland, C Reid, G Behan, D Bazou

Experts in our system

Hongzhou Zhang
Trinity College Dublin
Total Publications: 50