Journal Article


Hugh Garavan



substance related disorders psychology physiopathology cerebral cortex humans cognition cues physiology emotions awareness animals motivation drive anatomy histology

Insula and drug cravings. (2009)

Abstract This paper reviews the role of the insula in drug craving. Evidence is presented that drug craving may be a particular instance of the anterior insula's broader role in interoception and subjective feeling states similar, for example, to thirst and hunger. An important role for the insula in craving is supported by evidence of insular activity changing with satiety and with the top-down cognitive modulation of cravings. Cognitive processes involving the insula's role in awareness of one's own behaviour may also contribute to craving insofar as the avoidance of craving might require subjective awareness of the endogenous and exogenous cues that initiate it. Finally, some consideration is given to sex differences and developmental processes in craving.
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Hugh Garavan

Experts in our system

Hugh Garavan
Trinity College Dublin
Total Publications: 160