Type

Journal Article

Authors

Hugh Garavan
Ian H Robertson
Mark A. Bellgrove
Ruth Acheson
Claire T Tobin
Katherine A. Johnson
Wouter Braet

Subjects

Psychiatry

Topics
blood supply statistics as topic young adult aging attention neuropsychological tests physiology humans adult child adolescent reaction time brain mapping magnetic resonance imaging inhibition psychology discrimination psychology blood male brain oxygen

Functional developmental changes underlying response inhibition and error-detection processes. (2008)

Abstract This study examined the developmental trajectories associated with response inhibition and error processing as exemplar executive processes. We present fMRI data showing developmental changes to the functional networks underlying response inhibition and error-monitoring, comparing activation between adults and young adolescents performing the sustained attention to response task (SART). During successful inhibitions, we observed greater activation for the young adolescents than for the adults, in a widely distributed network including frontal, parietal and medial regions. When inhibition failed, however, adults showed increased activation compared to young adolescents in a number of regions, including bilateral parahippocampal gyrus, left and right lingual gyri, the right insula, and cerebellar regions. These differences largely remained even when the two groups were matched for performance, suggesting that performance differences are unlikely to be the driving factor behind these developmental differences. Instead, the neurodevelopmental trajectory of these important executive functions may reveal the basis for the immature executive functioning of the young adolescent.
Collections Ireland -> Trinity College Dublin -> PubMed

Full list of authors on original publication

Hugh Garavan, Ian H Robertson, Mark A. Bellgrove, Ruth Acheson, Claire T Tobin, Katherine A. Johnson, Wouter Braet

Experts in our system

1
Hugh Garavan
Trinity College Dublin
Total Publications: 160
 
2
Ian H Robertson
Trinity College Dublin
Total Publications: 157
 
3
Mark A. Bellgrove
Trinity College Dublin
Total Publications: 35
 
4
Katherine Johnson
Trinity College Dublin
Total Publications: 29