Journal Article


Mark A. Bellgrove
Katherine A. Johnson
Wouter Braet
Ciara M. Greene



physiology psychomotor performance humans schizophrenia cognition phenotype molecular biology magnetic resonance imaging psychology anatomy histology schizophrenic psychology genetics attention deficit disorder with hyperactivity mental disorders inhibition psychology brain memory autistic disorder pathology

Imaging the genetics of executive function. (2007)

Abstract Recent advances in neuroimaging technologies have allowed ever more detailed studies of the human brain. The combination of neuroimaging techniques with genetics may provide a more sensitive measure of the influence of genetic variants on cognitive function than behavioural measures alone. Here we present a review of functional magnetic resonance imaging (fMRI) studies of genetic links to executive functions, focusing on sustained attention, working memory and response inhibition. In addition to studies in the normal population, we also address findings from three clinical populations: schizophrenia, ADHD and autism spectrum disorders. While the findings in the populations studied do not always converge, they all point to the usefulness of neuroimaging techniques such as fMRI as potential endophenotypes for parsing the genetic aetiology of executive function.
Collections Ireland -> Trinity College Dublin -> PubMed

Full list of authors on original publication

Mark A. Bellgrove, Katherine A. Johnson, Wouter Braet, Ciara M. Greene

Experts in our system

Mark A. Bellgrove
Trinity College Dublin
Total Publications: 39
Katherine Johnson
Trinity College Dublin
Total Publications: 29
Ciara M. Greene
University College Cork
Total Publications: 26